iGMDRD765

Canonical SMILES: ONC(=O)c1cccc(c1)C(=O)Nc2ccccc2

InChI: InChI=1S/C14H12N2O3/c17-13(15-12-7-2-1-3-8-12)10-5-4-6-11(9-10)14(18)16-19/h1-9,19H,(H,15,17)(H,16,18)

InChI Key: NXHPVXNYPQJIOB-UHFFFAOYSA-N

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Standard Name
Pubchem CID
Drug Status
Standard NameBRD-K51490254
Pubchem CID71680900
Drug StatusAlone

Drug Targets:

HDAC6HDAC8

Drug-model tissue-cancer distribution: Bubble Plot

UTERUtissue: UTERU cancer: UTERUS model num: 0UTERUStissue: UTERUS cancer: undefined model num: 1LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: undefined model num: 1BREAStissue: BREAS cancer: BREAST model num: 0BREASTtissue: BREAST cancer: undefined model num: 1undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 5

Drug-gene pathway enrichments

9reactome: Signal Transduction5reactome: Disease4wikipathways: PI3K-Akt Signaling Pathway4reactome: Gene expression (Transcription)4wikipathways: Focal Adhesion-PI3K-Akt-mTOR-signaling pathway4reactome: RNA Polymerase II Transcription4reactome: Diseases of signal transduction4kegg: Pathways in cancer - Homo sapiens (human)4wikipathways: ESC Pluripotency Pathways4kegg: PI3K-Akt signaling pathway - Homo sapiens (human)

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
7514 XPO1 1
5159 PDGFRB 1
6794 STK11 1
5604 MAP2K1 1
Showing 1 to 4 of 6 rows

Gene in drug-gene network: Network Plot

Models in BRD-K51490254

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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