iGMDRD145

Canonical SMILES: CC(C)(CCCC(CC(=O)OC)(C(=O)OC1C2C3=CC4=C(C=C3CCN5C2(CCC5)C=C1OC)OCO4)O)O

InChI: InChI=1S/C29H39NO9/c1-27(2,33)8-5-10-29(34,16-23(31)36-4)26(32)39-25-22(35-3)15-28-9-6-11-30(28)12-7-18-13-20-21(38-17-37-20)14-19(18)24(25)28/h13-15,24-25,33-34H,5-12,16-17H2,1-4H3/t24-,25-,28+,29-/m1/s1

InChI Key: HYFHYPWGAURHIV-JFIAXGOJSA-N

Loading, please wait...
Standard Name
CHEMBL
Pubchem CID
DRUGBANK ID
Drug Status
Drug Type
Standard NameOmacetaxine mepesuccinate
CHEMBLCHEMBL46286
Pubchem CID285033
DRUGBANK IDDB04865
Drug StatusAlone
Drug TypeSmall Molecule


Drug-model tissue-cancer distribution: Bubble Plot

LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: undefined model num: 1BREAStissue: BREAS cancer: BREAST model num: 0BREASTtissue: BREAST cancer: undefined model num: 1undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 16

Drug-gene pathway enrichments

4reactome: Signal Transduction3reactome: Gene expression (Transcription)3reactome: RNA Polymerase II Transcription3reactome: Generic Transcription Pathway3reactome: Cell Cycle Checkpoints3reactome: Disease3reactome: DNA Repair3reactome: Cell Cycle2reactome: DNA Double-Strand Break Repair2kegg: Insulin signaling pathway - Homo sapiens (human)

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Loading, please wait...
Gene ID
Gene Name
Model Num.
7514 XPO1 1
2956 MSH6 1
8266 UBL4A 1
11200 CHEK2 1
Showing 1 to 4 of 10 rows

Gene in drug-gene network: Network Plot

Models in Omacetaxine mepesuccinate

Loading, please wait...
Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

​​​​

SITE
DATATYPES
CLASSFICATION
Map

Copyright © 2018 Modellab | All Rights Reserved

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.