iGMDRD218

Canonical SMILES: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F

InChI: InChI=1S/C14H11F3N2OS/c15-14(16,17)9-3-1-8(2-4-9)12-18-11-5-6-21-7-10(11)13(20)19-12/h1-4H,5-7H2,(H,18,19,20)

InChI Key: KLGQSVMIPOVQAX-UHFFFAOYSA-N

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Standard Name
CHEMBL
Pubchem CID
Drug Status
Drug Type
Standard NameXAV 939
CHEMBLCHEMBL1086580
Pubchem CID2726820
Drug StatusAlone
Drug TypeSmall Molecule


Drug Pathways:

WNT signaling

Drug-model tissue-cancer distribution: Bubble Plot

BREAStissue: BREAS cancer: BREAST model num: 0BREASTtissue: BREAST cancer: Breast Carcinoma model num: 2undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 1STOMACtissue: STOMAC cancer: STOMACH model num: 0STOMACHtissue: STOMACH cancer: Esophageal Adenocarcinoma (ESCA) model num: 1HEAD_NECtissue: HEAD_NEC cancer: HEAD_NECK model num: 0HEAD_NECKtissue: HEAD_NECK cancer: Head and Neck Squamous Cell Carcinoma (HNSC) model num: 1KIDNEtissue: KIDNE cancer: KIDNEY model num: 0KIDNEYtissue: KIDNEY cancer: Renal Clear Cell Carcinoma (CCRCC) model num: 1LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: Lung Adenocarcinoma (LUAD) model num: 1OVARtissue: OVAR cancer: OVARY model num: 0OVARYtissue: OVARY cancer: Ovarian Cancer model num: 1PANCREAtissue: PANCREA cancer: PANCREAS model num: 0PANCREAStissue: PANCREAS cancer: Pancreatic Adenocarcinoma (PAAD) model num: 1

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
7428 VHL 1
7157 TP53 1
6794 STK11 1
546 ATRX 1
Showing 1 to 4 of 10 rows

Gene in drug-gene network: Network Plot

Models in XAV 939

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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