iGMDRD326
Canonical SMILES: C1=CC=C(C=C1)NS(=O)(=O)C2=CC=CC(=C2)C=CC(=O)NO
InChI: InChI=1S/C15H14N2O4S/c18-15(16-19)10-9-12-5-4-8-14(11-12)22(20,21)17-13-6-2-1-3-7-13/h1-11,17,19H,(H,16,18)/b10-9+
InChI Key: NCNRHFGMJRPRSK-MDZDMXLPSA-N
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Standard Name | CHEMBL | Pubchem CID | DRUGBANK ID | Drug Status | Drug Type |
|---|---|---|---|---|---|
Standard NameBelinostat (PXD101) CHEMBLCHEMBL408513 Pubchem CID6918640 DRUGBANK IDDB05015 Drug StatusAlone Drug TypeSmall Molecule | |||||
Drug Class:
AmidesAminesAntineoplastic AgentsAntineoplastic and Immunomodulating AgentsCarboxylic AcidsCytochrome P-450 CYP1A2 InducersCytochrome P-450 CYP1A2 Inducers (weak)Cytochrome P-450 Enzyme InducersCytochrome P-450 Enzyme InhibitorsEnzyme InhibitorsHistone Deacetylase InhibitorsHydroxy AcidsHydroxylaminesImmunosuppressive AgentsMyelosuppressive AgentsP-glycoprotein/ABCB1 SubstratesSulfonesSulfur CompoundsDrug Targets:
HDAC1 (Q13547)Drug Pathways:
Chromatin histone acetylationDrug-model tissue-cancer distribution: Bubble Plot
Drug-gene pathway enrichments
Drug-gene GO enrichments
Drug-Gene: Aster Plot
Gene in drug-gene network: Network Plot
Models in Belinostat (PXD101)
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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