iGMDRD327
Canonical SMILES: CC1=C(C2=CC=CC=C2N1)CCNCC3=CC=C(C=C3)C=CC(=O)NO
InChI: InChI=1S/C21H23N3O2/c1-15-18(19-4-2-3-5-20(19)23-15)12-13-22-14-17-8-6-16(7-9-17)10-11-21(25)24-26/h2-11,22-23,26H,12-14H2,1H3,(H,24,25)/b11-10+
InChI Key: FPOHNWQLNRZRFC-ZHACJKMWSA-N
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Standard Name | CHEMBL | Pubchem CID | DRUGBANK ID | Drug Status | Drug Type |
|---|---|---|---|---|---|
Standard NameLBH-589 CHEMBLCHEMBL483254 Pubchem CID6918840 DRUGBANK IDDB06603 Drug StatusAlone Drug TypeSmall Molecule | |||||
Drug Class:
AminesAntineoplastic AgentsAntineoplastic and Immunomodulating AgentsCarboxylic AcidsCytochrome P-450 CYP2D6 InhibitorsCytochrome P-450 CYP2D6 Inhibitors (moderate)Cytochrome P-450 Enzyme InhibitorsEnzyme InhibitorsHeterocyclic CompoundsHeterocyclic Compounds, 2-RingHistone Deacetylase InhibitorsHydroxy AcidsHydroxylaminesImmunosuppressive AgentsModerate Risk QTc-Prolonging AgentsP-glycoprotein/ABCB1 SubstratesQTc Prolonging AgentsDrug-model tissue-cancer distribution: Bubble Plot
Drug-gene pathway enrichments
Drug-gene GO enrichments
Drug-Gene: Aster Plot
Gene in drug-gene network: Network Plot
Models in LBH-589
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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