iGMDRD370

Canonical SMILES: C1=CC(=CC=C1C2=CC(=C(S2)NC(=O)N)C(=O)N)F

InChI: InChI=1S/C12H10FN3O2S/c13-7-3-1-6(2-4-7)9-5-8(10(14)17)11(19-9)16-12(15)18/h1-5H,(H2,14,17)(H3,15,16,18)

InChI Key: SAYGKHKXGCPTLX-UHFFFAOYSA-N

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Standard Name
CHEMBL
Pubchem CID
Drug Status
Drug Type
Standard NameTPCA-1
CHEMBLCHEMBL257167
Pubchem CID9903790
Drug StatusAlone
Drug TypeSmall Molecule

Drug Targets:

IKK

Drug Pathways:

Other, kinases

Drug-model tissue-cancer distribution: Bubble Plot

SKItissue: SKI cancer: SKIN model num: 0SKINtissue: SKIN cancer: undefined model num: 1BREAStissue: BREAS cancer: BREAST model num: 0BREASTtissue: BREAST cancer: undefined model num: 1undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 12BLADDEtissue: BLADDE cancer: BLADDER model num: 0BLADDERtissue: BLADDER cancer: Bladder Cancer model num: 1BONtissue: BON cancer: BONE model num: 0BONEtissue: BONE cancer: Acute Myeloid Leukemia (AML) model num: 2LYMPtissue: LYMP cancer: LYMPH model num: 0LYMPHtissue: LYMPH cancer: Diffuse Large B-Cell Lymphoma (DLBCL) model num: 1

Drug-gene pathway enrichments

8reactome: Signal Transduction7reactome: Gene expression (Transcription)7reactome: RNA Polymerase II Transcription7reactome: Generic Transcription Pathway4wikipathways: miR-targeted genes in lymphocytes - TarBase3wikipathways: miR-targeted genes in epithelium - TarBase3kegg: HTLV-I infection - Homo sapiens (human)3kegg: MicroRNAs in cancer - Homo sapiens (human)3kegg: Hepatocellular carcinoma - Homo sapiens (human)3kegg: Pathways in cancer - Homo sapiens (human)

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
7514 XPO1 1
8289 ARID1A 1
9757 KMT2B 2
4851 NOTCH1 1
Showing 1 to 4 of 10 rows

Gene in drug-gene network: Network Plot

Models in TPCA-1

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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