iGMDRD426

Canonical SMILES: CCCC(C1=CC=CC=C1)NC(=O)C(=CC2=NC(=CC=C2)Br)C#N

InChI: InChI=1S/C19H18BrN3O/c1-2-7-17(14-8-4-3-5-9-14)23-19(24)15(13-21)12-16-10-6-11-18(20)22-16/h3-6,8-12,17H,2,7H2,1H3,(H,23,24)/b15-12+/t17-/m0/s1

InChI Key: LIDOPKHSVQTSJY-VMEIHUARSA-N

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Standard Name
Pubchem CID
Drug Status
Drug Type
Standard NameWP1130
Pubchem CID11222800
Drug StatusAlone
Drug TypeSmall Molecule

Drug Targets:

UCHL5USP14USP5USP9X

Drug-model tissue-cancer distribution: Bubble Plot

OVARtissue: OVAR cancer: OVARY model num: 0OVARYtissue: OVARY cancer: undefined model num: 1LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: undefined model num: 2undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 11

Drug-gene pathway enrichments

6reactome: Signal Transduction4reactome: Disease3reactome: MAPK family signaling cascades3netpath: EGFR13reactome: Signaling by Receptor Tyrosine Kinases2reactome: PIP3 activates AKT signaling2reactome: Signaling by ERBB22reactome: SHC1 events in ERBB2 signaling2wikipathways: Signaling Pathways in Glioblastoma2kegg: Calcium signaling pathway - Homo sapiens (human)

Drug-gene GO enrichments

9MF: protein binding7CC: cytoplasm6CC: integral component of plasma membrane6CC: nucleus5CC: receptor complex5MF: protein tyrosine kinase activity5CC: plasma membrane5CC: nucleoplasm4MF: ATP binding4MF: growth factor binding

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
7514 XPO1 1
8266 UBL4A 1
6598 SMARCB1 1
5159 PDGFRB 1
Showing 1 to 4 of 9 rows

Gene in drug-gene network: Network Plot

Models in WP1130

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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