iGMDRD473

Canonical SMILES: C1CC(=NO)C2=C1C=C(C=C2)C3=CN(N=C3C4=CC=NC=C4)CCO

InChI: InChI=1S/C19H18N4O2/c24-10-9-23-12-17(19(21-23)13-5-7-20-8-6-13)15-1-3-16-14(11-15)2-4-18(16)22-25/h1,3,5-8,11-12,24-25H,2,4,9-10H2/b22-18+

InChI Key: DEZZLWQELQORIU-RELWKKBWSA-N

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Standard Name
Pubchem CID
Drug Status
Drug Type
Standard NameGDC-0879
Pubchem CID11717000
Drug StatusAlone
Drug TypeSmall Molecule

Drug-model tissue-cancer distribution: Bubble Plot

SKItissue: SKI cancer: SKIN model num: 0SKINtissue: SKIN cancer: undefined model num: 1LIVEtissue: LIVE cancer: LIVER model num: 0LIVERtissue: LIVER cancer: undefined model num: 1undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 7

Drug-gene pathway enrichments

7reactome: Signal Transduction3kegg: MicroRNAs in cancer - Homo sapiens (human)3kegg: Human papillomavirus infection - Homo sapiens (human)3wikipathways: Notch Signaling Pathway3reactome: RNA Polymerase II Transcription3reactome: Gene expression (Transcription)3reactome: Generic Transcription Pathway3reactome: Cell Cycle Checkpoints3reactome: Cell Cycle3reactome: Disease

Drug-gene GO enrichments

9CC: cytosol6MF: protein binding4CC: nucleoplasm4BP: positive regulation of apoptotic process4CC: plasma membrane4CC: nucleus3CC: cytoplasm3BP: protein export from nucleus2BP: ribosomal large subunit export from nucleus2MF: nuclear export signal receptor activity

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
4854 NOTCH3 1
7514 XPO1 1
57580 PREX1 1
472 ATM 1
Showing 1 to 4 of 6 rows

Gene in drug-gene network: Network Plot

Models in GDC-0879

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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