iGMDRD479

Canonical SMILES: CC1(CCCN1)C2=NC3=C(C=CC=C3N2)C(=O)N

InChI: InChI=1S/C13H16N4O/c1-13(6-3-7-15-13)12-16-9-5-2-4-8(11(14)18)10(9)17-12/h2,4-5,15H,3,6-7H2,1H3,(H2,14,18)(H,16,17)/t13-/m1/s1

InChI Key: JNAHVYVRKWKWKQ-CYBMUJFWSA-N

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Standard Name
CHEMBL
Pubchem CID
DRUGBANK ID
Drug Status
Drug Type
Standard NameVeliparib
CHEMBLCHEMBL506871
Pubchem CID11960500
DRUGBANK IDDB07232
Drug StatusAlone
Drug TypeSmall Molecule



Drug Pathways:

Genome integrity

Drug-model tissue-cancer distribution: Bubble Plot

LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: undefined model num: 1BREAStissue: BREAS cancer: BREAST model num: 0BREASTtissue: BREAST cancer: undefined model num: 9BREASTtissue: BREAST cancer: Invasive Breast Carcinoma (BRCA) model num: 2BREASTtissue: BREAST cancer: Breast Carcinoma model num: 2undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 2

Drug-gene pathway enrichments

4wikipathways: Signaling Pathways in Glioblastoma4reactome: Metabolism of proteins4reactome: Gene expression (Transcription)4reactome: DNA Repair4reactome: RNA Polymerase II Transcription4reactome: Generic Transcription Pathway4reactome: Signal Transduction3reactome: HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)3kegg: Fanconi anemia pathway - Homo sapiens (human)3reactome: DNA Double-Strand Break Repair

Drug-gene GO enrichments

12MF: protein binding12CC: nucleoplasm8BP: positive regulation of transcription, DNA-templated7CC: nucleus7BP: positive regulation of transcription by RNA polymerase II7CC: cytosol5MF: transcription coactivator activity5CC: plasma membrane5BP: mismatch repair5BP: double-strand break repair via homologous recombination

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
2956 MSH6 1
2625 GATA3 1
25937 WWTR1 1
672 BRCA1 2
Showing 1 to 4 of 10 rows

Gene in drug-gene network: Network Plot

Models in Veliparib

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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