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HSP90 inhibitor
iGMDRD920
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Standard Name
Drug Status
Drug Type
Standard Name
HSP90 inhibitor
Drug Status
Family
Drug Type
undefined
Drug Class:
Kinase Inhibitor
Protein Kinase Inhibitors
Antineoplastic Agents
Antineoplastic Agents, Phytogenic
Drug-model tissue-cancer distribution: Bubble Plot
LUN
tissue: LUN cancer: LUNG model num: 0
LUNG
tissue: LUNG cancer: Lung Adenocarcinoma (LUAD) model num: 2
LUNG
tissue: LUNG cancer: Lung Cancer model num: 26
LUNG
tissue: LUNG cancer: Adenoid Cystic Carcinoma of the Lung (LUACC) model num: 2
SKI
tissue: SKI cancer: SKIN model num: 0
SKIN
tissue: SKIN cancer: Cutaneous Melanoma (SKCM) model num: 2
SKIN
tissue: SKIN cancer: Melanoma (MEL) model num: 2
BREAS
tissue: BREAS cancer: BREAST model num: 0
BREAST
tissue: BREAST cancer: Invasive Breast Carcinoma (BRCA) model num: 1
BREAST
tissue: BREAST cancer: Breast Carcinoma model num: 1
SOFT_TISSU
tissue: SOFT_TISSU cancer: SOFT_TISSUE model num: 0
SOFT_TISSUE
tissue: SOFT_TISSUE cancer: Gastrointestinal Stromal Tumor (GIST) model num: 7
BLOO
tissue: BLOO cancer: BLOOD model num: 0
BLOOD
tissue: BLOOD cancer: Myeloproliferative Neoplasm (MPN) model num: 2
BLOOD
tissue: BLOOD cancer: Leukemia (LEUK) model num: 1
BRAI
tissue: BRAI cancer: BRAIN model num: 0
BRAIN
tissue: BRAIN cancer: Meningioma (MNG) model num: 2
OTHE
tissue: OTHE cancer: OTHER model num: 0
OTHER
tissue: OTHER cancer: Cancer of Unknown Primary (CUP) model num: 4
PN
tissue: PN cancer: PNS model num: 0
PNS
tissue: PNS cancer: Malignant Peripheral Nerve Sheath Tumor (MPNST) model num: 1
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Drug-gene pathway enrichments
15
reactome: Signal Transduction
11
reactome: Signaling by Receptor Tyrosine Kinases
8
kegg: MAPK signaling pathway - Homo sapiens (human)
7
wikipathways: Signaling Pathways in Glioblastoma
7
reactome: MAPK1/MAPK3 signaling
7
reactome: Disease
7
kegg: Pathways in cancer - Homo sapiens (human)
7
reactome: Diseases of signal transduction
7
reactome: MAPK family signaling cascades
7
reactome: RAF/MAP kinase cascade
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Drug-gene GO enrichments
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Drug-Gene: Aster Plot
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Gene ID
Gene Name
Model Num.
4771
NF2
2
2064
ERBB2
2
6098
ROS1
1
7157
TP53
4
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Gene in drug-gene network: Network Plot
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Models in HSP90 inhibitor
Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found
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