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iGMDRD157

Canonical SMILES: CC1C(C(C(C(O1)OC2CC(C3(C4C(CCC3(C2)O)C5(CCC(C5(CC4O)C)C6=CC(=O)OC6)O)CO)O)O)O)O

InChI: InChI=1S/C29H44O12/c1-13-22(34)23(35)24(36)25(40-13)41-15-8-19(32)28(12-30)21-17(3-5-27(28,37)9-15)29(38)6-4-16(14-7-20(33)39-11-14)26(29,2)10-18(21)31/h7,13,15-19,21-25,30-32,34-38H,3-6,8-12H2,1-2H3/t13-,15-,16+,17+,18+,19+,21+,22-,23+,24+,25-,26+,27-,28+,29-/m0/s1

InChI Key: LPMXVESGRSUGHW-HBYQJFLCSA-N

Standard Name	CHEMBL	Pubchem CID	KEGG Drug ID	DRUGBANK ID	Drug Status	Drug targets (TTD)	Drug Type
Ouabain	CHEMBL222863	439501	D00112	DB01092	Alone	DAP000465	Small Molecule

Drug Class:

Carbohydrates Cardanolides Cardenolides Cardiac Glycosides Cardiac Therapy Cardiotonic Agents Cardiovascular Agents Cardiovascular System Enzyme Inhibitors Glycosides Polycyclic Compounds Protective Agents Specialty Uses of Chemicals Steroids Strophanthins Strophanthus Glycosides

Drug Targets:

ATP1A1 (P05023)ATP1A2 (P50993)ATP1A3 (P13637)ATP1A4 ATP1B1 ATP1B2 ATP1B3 ATP1B4

Drug Pathways:

Cardiac muscle contraction Adrenergic signaling in cardiomyocytes

Drug Synonyms:

G-Strophanthin (JAN)Ouabain Ouabain octahydrate

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Gene ID	Gene Name	Model Num.
7514	XPO1	1
2956	MSH6	1
8266	UBL4A	1
7158	TP53BP1	1
3791	KDR	1
4086	SMAD1	1
1978	EIF4EBP1	1
7301	TYRO3	1
9223	MAGI1	1
2065	ERBB3	1
94	ACVRL1	1

Gene in drug-gene network: Network Plot

Models in Ouabain

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Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.