iGMDRD468

Canonical SMILES: CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(C)(C)C#N)NC3=CC4=C(C=C3)N=CN(C4=O)C

InChI: InChI=1S/C27H25N5O2/c1-17-8-9-21(31-25(33)18-6-5-7-19(12-18)27(2,3)15-28)14-24(17)30-20-10-11-23-22(13-20)26(34)32(4)16-29-23/h5-14,16,30H,1-4H3,(H,31,33)

InChI Key: ZGBGPEDJXCYQPH-UHFFFAOYSA-N

Standard NameCHEMBLPubchem CIDDrug StatusDrug Type
AZ628CHEMBL2144069 11676800AloneSmall Molecule

Drug Targets:

BRAF

Drug Pathways:

ERK MAPK signaling

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
3845KRAS2
25937WWTR11
238ALK1
1029CDKN2A1
7157TP531
3673ITGA21
4292MLH11
673BRAF4
201163FLCN1
5925RB11
4893NRAS1
4763NF11

Gene in drug-gene network: Network Plot

Models in AZ628

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