BAZ2B


Summary: This gene belongs to the bromodomain gene family. Members of this gene family encode proteins that are integral components of chromatin remodeling complexes. The encoded protein showed strong preference for the activating H3K14Ac mark in a histone peptide screen, suggesting a potential role in transcriptional activation. This gene may be associated with susceptibility to sudden cardiac death (SCD). [provided by RefSeq, Aug 2016].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
bromodomain adjacent to zinc finger domain 2BMIM:605683Ensembl:ENSG00000226266HGNC:HGNC:963PA252732q24.2

GO terms in BAZ2B


Term TypeEvidence TypeGO Term IDGO Des.
MFIEAGO:0003677DNA binding
MFIPIGO:0005515protein binding
MFIEAGO:0046872metal ion binding
BPTASGO:0006338chromatin remodeling
BPIEAGO:0006351transcription, DNA-templated
BPNASGO:0006357regulation of transcription by RNA polymerase II
CCIEAGO:0005634nucleus

Gene expression in normal tissue: BAZ2B

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in BAZ2B


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD126Tipifarnib1
iGMDRD467Motesanib1
iGMDRD434BMS-5369241
iGMDRD532Olaparib1
iGMDRD283Bosutinib1
iGMDRD498GW441756X1
iGMDRD119Temsirolimus1
iGMDRD775NCGC00346967-011
iGMDRD190Nilotinib1
iGMDRD454JNK Inhibitor VIII1

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in BAZ2B

​​​​