iGMDRD478


Canonical SMILES: CC1(CCCN1)C2=NC3=C(C=CC=C3N2)C(=O)N

InChI: InChI=1S/C13H16N4O/c1-13(6-3-7-15-13)12-16-9-5-2-4-8(11(14)18)10(9)17-12/h2,4-5,15H,3,6-7H2,1H3,(H2,14,18)(H,16,17)/t13-/m1/s1

InChI Key: JNAHVYVRKWKWKQ-CYBMUJFWSA-N

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Standard Name
CHEMBL
Pubchem CID
DRUGBANK ID
Drug Status
Drug Type
Standard NameABT-888
Pubchem CID11960500
DRUGBANK IDDB07232
Drug StatusAlone
Drug TypeSmall Molecule



Drug Pathways:

Genome integrity

Drug-model tissue-cancer distribution: Bubble Plot

BREAStissue: BREAS cancer: BREAST model num: 0BREASTtissue: BREAST cancer: undefined model num: 1undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 9BOWEtissue: BOWE cancer: BOWEL model num: 0BOWELtissue: BOWEL cancer: undefined model num: 1SKItissue: SKI cancer: SKIN model num: 0SKINtissue: SKIN cancer: undefined model num: 1SKINtissue: SKIN cancer: Cutaneous Melanoma (SKCM) model num: 1LYMPtissue: LYMP cancer: LYMPH model num: 0LYMPHtissue: LYMPH cancer: Diffuse Large B-Cell Lymphoma (DLBCL) model num: 1HEAD_NECtissue: HEAD_NEC cancer: HEAD_NECK model num: 0HEAD_NECKtissue: HEAD_NECK cancer: Head and Neck Squamous Cell Carcinoma (HNSC) model num: 1BONtissue: BON cancer: BONE model num: 0BONEtissue: BONE cancer: Acute Myeloid Leukemia (AML) model num: 1

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
3658 IREB2 1
4771 NF2 1
9757 KMT2B 1
25937 WWTR1 1
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Gene in drug-gene network: Network Plot

Models in ABT-888

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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