OXSR1


Summary: The product of this gene belongs to the Ser/Thr protein kinase family of proteins. It regulates downstream kinases in response to environmental stress, and may play a role in regulating the actin cytoskeleton. [provided by RefSeq, Jul 2008].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
oxidative stress responsive 1MIM:604046Ensembl:ENSG00000172939HGNC:HGNC:8508PA1349732073p22.2

GO terms in OXSR1


Term TypeEvidence TypeGO Term IDGO Des.
CCIBAGO:0005737cytoplasm
CCIDAGO:0005829cytosol
CCHDAGO:0070062extracellular exosome
BPIDAGO:0006468protein phosphorylation
BPIEAGO:0006979response to oxidative stress
BPIBAGO:0007346regulation of mitotic cell cycle
BPIDAGO:0018107peptidyl-threonine phosphorylation
BPIBAGO:0023014signal transduction by protein phosphorylation
BPIBAGO:0032147activation of protein kinase activity
BPIDAGO:0035556intracellular signal transduction
BPIEAGO:0071476cellular hypotonic response
BPIEAGO:1901017negative regulation of potassium ion transmembrane transporter activity
MFIDAGO:0000287magnesium ion binding
MFIBAGO:0004674protein serine/threonine kinase activity
MFIDAGO:0004674protein serine/threonine kinase activity
MFIPIGO:0005515protein binding
MFIDAGO:0005524ATP binding
MFIPIGO:0042802identical protein binding

Gene expression in normal tissue: OXSR1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in OXSR1


DatabasePathway IDPathway Des.
pharmgkbPA165984799Diuretics Pathway, Pharmacodynamics

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD60Quinoclamine2
iGMDRD61Kinetin riboside1
iGMDRD366PI-1036
iGMDRD562Navitoclax3
iGMDRD506Fedratinib6
iGMDRD399Selumetinib2
iGMDRD286Nsc 6328395
iGMDRD434BMS-5369243
iGMDRD255SB2250023
iGMDRD137Indisulam2

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in OXSR1

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