iGMDRD244

Canonical SMILES: CCN1CCN(CC1)C(C2=CC=C(C=C2)C(F)(F)F)C3=C(C4=C(C=CC=N4)C=C3)O

InChI: InChI=1S/C23H24F3N3O/c1-2-28-12-14-29(15-13-28)21(17-5-8-18(9-6-17)23(24,25)26)19-10-7-16-4-3-11-27-20(16)22(19)30/h3-11,21,30H,2,12-15H2,1H3

InChI Key: NGAPBLRRJSKIRT-UHFFFAOYSA-N

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Standard Name
Pubchem CID
Drug Status
Drug Type
Standard NameML311
Pubchem CID3384730
Drug StatusAlone
Drug TypeSmall Molecule

Drug Targets:

MCL1

Drug-model tissue-cancer distribution: Bubble Plot

UTERUtissue: UTERU cancer: UTERUS model num: 0UTERUStissue: UTERUS cancer: undefined model num: 1OVARtissue: OVAR cancer: OVARY model num: 0OVARYtissue: OVARY cancer: undefined model num: 1LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: undefined model num: 1LIVEtissue: LIVE cancer: LIVER model num: 0LIVERtissue: LIVER cancer: undefined model num: 2undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 16

Drug-gene pathway enrichments

8reactome: Signal Transduction4reactome: Signaling by Receptor Tyrosine Kinases4reactome: Disease3wikipathways: Focal Adhesion3wikipathways: PI3K-Akt Signaling Pathway3reactome: Signaling by TGF-beta family members3kegg: Focal adhesion - Homo sapiens (human)3kegg: Pathways in cancer - Homo sapiens (human)3reactome: Extracellular matrix organization3reactome: Cell Cycle

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
7514 XPO1 1
2956 MSH6 1
5159 PDGFRB 1
5834 PYGB 1
Showing 1 to 4 of 11 rows rows per page

Gene in drug-gene network: Network Plot

Models in ML311

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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