iGMDRD333

Canonical SMILES: C1=CC=C(C(=C1)C(=C(N)SC2=CC=C(C=C2)N)C#N)C(F)(F)F

InChI: InChI=1S/C16H12F3N3S/c17-16(18,19)14-4-2-1-3-12(14)13(9-20)15(22)23-11-7-5-10(21)6-8-11/h1-8H,21-22H2/b15-13+

InChI Key: JLOXTZFYJNCPIS-FYWRMAATSA-N

Standard NameCHEMBLPubchem CIDDrug StatusDrug Type
MEK InhibitorCHEMBL261237 9549280FamilySmall Molecule

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
3845KRAS59
4771NF22
5605MAP2K210
6794STK116
5604MAP2K145
369ARAF1
1956EGFR1
673BRAF17
2767GNA118
5728PTEN5
2776GNAQ4
4893NRAS28
2065ERBB36
4763NF114
3265HRAS6

Gene in drug-gene network: Network Plot

Models in MEK Inhibitor

​​​​

SITE
DATATYPES
CLASSFICATION
Map

Copyright © 2018 Modellab | All Rights Reserved

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.