iGMDRD404

Canonical SMILES: C1=CC(=C(C=C1I)F)NC2=C(C(=C(C=C2C(=O)NOCC(CO)O)Br)F)F

InChI: InChI=1S/C16H13BrF3IN2O4/c17-10-4-9(16(26)23-27-6-8(25)5-24)15(14(20)13(10)19)22-12-2-1-7(21)3-11(12)18/h1-4,8,22,24-25H,5-6H2,(H,23,26)

InChI Key: XXSSGBYXSKOLAM-UHFFFAOYSA-N

Standard NamePubchem CIDDrug StatusDrug Type
PD31808810231300AloneSmall Molecule

Drug Targets:

MAP2K1MAP2K2

Drug Pathways:

ERK MAPK signaling

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
7514XPO11
57580PREX11
6598SMARCB11
4170MCL11
1846DUSP41
369ARAF1
1869E2F11
5054SERPINE11
4780NFE2L21

Gene in drug-gene network: Network Plot

Models in PD318088

​​​​

SITE
DATATYPES
CLASSFICATION
Map

Copyright © 2018 Modellab | All Rights Reserved

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.