iGMDRD526

Canonical SMILES: C1COCCN1CCOC2=CC=C(C=C2)C3=CN=C(C=C3)CC(=O)NCC4=CC=CC=C4

InChI: InChI=1S/C26H29N3O3/c30-26(28-19-21-4-2-1-3-5-21)18-24-9-6-23(20-27-24)22-7-10-25(11-8-22)32-17-14-29-12-15-31-16-13-29/h1-11,20H,12-19H2,(H,28,30)

InChI Key: HUNGUWOZPQBXGX-UHFFFAOYSA-N

Loading, please wait...
Standard Name
Pubchem CID
Drug Status
Drug Type
Standard NameKX2-391
Pubchem CID23635300
Drug StatusAlone
Drug TypeSmall Molecule

Drug-model tissue-cancer distribution: Bubble Plot

LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: undefined model num: 2LIVEtissue: LIVE cancer: LIVER model num: 0LIVERtissue: LIVER cancer: undefined model num: 2undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 14

Drug-gene pathway enrichments

5reactome: Signal Transduction4kegg: PI3K-Akt signaling pathway - Homo sapiens (human)4wikipathways: PI3K-Akt Signaling Pathway3reactome: Signaling by Receptor Tyrosine Kinases3netpath: EGFR13wikipathways: Focal Adhesion-PI3K-Akt-mTOR-signaling pathway3reactome: Metabolism of proteins2pharmgkb: Vemurafenib Pathway, Pharmacodynamics2kegg: MAPK signaling pathway - Homo sapiens (human)2kegg: Ras signaling pathway - Homo sapiens (human)

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Loading, please wait...
Gene ID
Gene Name
Model Num.
2956 MSH6 1
4170 MCL1 1
5159 PDGFRB 1
5834 PYGB 1
Showing 1 to 4 of 9 rows

Gene in drug-gene network: Network Plot

Models in KX2-391

Loading, please wait...
Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

​​​​

SITE
DATATYPES
CLASSFICATION
Map

Copyright © 2018 Modellab | All Rights Reserved

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.