iGMDRD75

Canonical SMILES: CCC(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O)C

InChI: InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1

InChI Key: PCZOHLXUXFIOCF-BXMDZJJMSA-N

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Standard Name
CHEMBL
Pubchem CID
KEGG Drug ID
DRUGBANK ID
Drug Status
Drug targets (TTD)
Drug Type
Standard NameLovastatin
CHEMBLCHEMBL503
Pubchem CID53232
KEGG Drug IDD00359
DRUGBANK IDDB00227
Drug StatusAlone
Drug targets (TTD)DAP000551
Drug TypeSmall Molecule

Drug Class:

Anticholesteremic AgentsCardiovascular SystemCombined Inhibitors of CYP3A4 and P-glycoproteinCombined Inhibitors of CYP3A4 and P-glycoprotein (Moderate)CYP3A Substrates (Sensitive)Cytochrome P-450 CYP3A InhibitorsCytochrome P-450 CYP3A SubstratesCytochrome P-450 CYP3A4 InhibitorsCytochrome P-450 CYP3A4 Inhibitors (moderate)Cytochrome P-450 CYP3A4 SubstratesCytochrome P-450 CYP3A5 SubstratesCytochrome P-450 CYP3A7 SubstratesCytochrome P-450 Enzyme InducersCytochrome P-450 Enzyme InhibitorsEnzyme InhibitorsHydrocarbonsHydrocarbons, AromaticHydrocarbons, CyclicHydroxymethylglutaryl-CoA Reductase InhibitorsHypolipidemic AgentsLipid Modifying AgentsLipid Modifying Agents, PlainLipid Regulating AgentsNaphthalenesNoxaeOATP1B1/SLCO1B1 SubstratesP-glycoprotein/ABCB1 InhibitorsP-glycoprotein/ABCB1 SubstratesPolycyclic CompoundsPolycyclic Hydrocarbons, AromaticToxic ActionsUGT1A1 Substrates



Drug-model tissue-cancer distribution: Bubble Plot

BOWEtissue: BOWE cancer: BOWEL model num: 0BOWELtissue: BOWEL cancer: undefined model num: 1BREAStissue: BREAS cancer: BREAST model num: 0BREASTtissue: BREAST cancer: undefined model num: 2LIVEtissue: LIVE cancer: LIVER model num: 0LIVERtissue: LIVER cancer: undefined model num: 1undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 16

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
7514 XPO1 1
10987 COPS5 1
4771 NF2 1
2625 GATA3 1
Showing 1 to 4 of 11 rows rows per page

Gene in drug-gene network: Network Plot

Models in Lovastatin

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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