iGMDRD967


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Standard Name
DRUGBANK ID
Drug Status
Drug Type
Standard NamePanitumumab
DRUGBANK IDDB01269
Drug StatusAlone
Drug TypeBiotech

Drug Targets:

EGFR (P00533)

Drug-model tissue-cancer distribution: Bubble Plot

BOWEtissue: BOWE cancer: BOWEL model num: 0BOWELtissue: BOWEL cancer: Colorectal Adenocarcinoma (COADREAD) model num: 17BOWELtissue: BOWEL cancer: Colorectal Cancer model num: 65BOWELtissue: BOWEL cancer: Mucinous Adenocarcinoma of the Colon and Rectum (MACR) model num: 1HEAD_NECtissue: HEAD_NEC cancer: HEAD_NECK model num: 0HEAD_NECKtissue: HEAD_NECK cancer: Head and Neck Squamous Cell Carcinoma (HNSC) model num: 2

Drug-gene pathway enrichments

19reactome: Signal Transduction14reactome: Signaling by Receptor Tyrosine Kinases12reactome: Disease11reactome: Diseases of signal transduction11reactome: Signaling by ERBB210kegg: Pathways in cancer - Homo sapiens (human)9kegg: PI3K-Akt signaling pathway - Homo sapiens (human)9kegg: Hepatocellular carcinoma - Homo sapiens (human)9kegg: Colorectal cancer - Homo sapiens (human)9kegg: ErbB signaling pathway - Homo sapiens (human)

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
3845 KRAS 24
55294 FBXW7 1
2064 ERBB2 1
1029 CDKN2A 2
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Gene in drug-gene network: Network Plot

Models in Panitumumab

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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