iGMDRD983

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Standard Name
Drug Status
Drug Type
Standard NamePI3K pathway inhibitor
Drug StatusFamily
Drug Typeundefined

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

24reactome: Signal Transduction18reactome: Signaling by Receptor Tyrosine Kinases13reactome: Hemostasis12reactome: Immune System12reactome: Signaling by NTRKs11kegg: Pathways in cancer - Homo sapiens (human)11reactome: Disease11reactome: Signaling by GPCR11reactome: Signaling by VEGF11reactome: GPCR downstream signalling

Drug-gene GO enrichments

17CC: plasma membrane16CC: cytoplasm14CC: cytosol13MF: protein binding12MF: protein serine/threonine kinase activity8BP: phosphatidylinositol 3-kinase signaling8BP: platelet activation7MF: ATP binding7CC: nucleus7MF: GTPase activity

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
3845 KRAS 19
5295 PIK3R1 2
207 AKT1 2
5290 PIK3CA 55
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Gene in drug-gene network: Network Plot

Models in PI3K pathway inhibitor

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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