JUN


Summary: This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. [provided by RefSeq, Jul 2008].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
Jun proto-oncogene, AP-1 transcription factor subunitMIM:165160Ensembl:ENSG00000177606HGNC:HGNC:6204PA300061p32.1

GO terms in JUN


Term TypeEvidence TypeGO Term IDGO Des.
MFIBAGO:0000978RNA polymerase II proximal promoter sequence-specific DNA binding
MFIDAGO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding
MFIBAGO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding
MFICGO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding
MFISAGO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding
MFISMGO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding
MFNASGO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding
MFIMPGO:0000982transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
MFIEAGO:0001077transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
MFIPIGO:0001102RNA polymerase II activating transcription factor binding
MFICGO:0001190transcriptional activator activity, RNA polymerase II transcription factor binding
MFTASGO:0003677DNA binding
MFIEAGO:0003682chromatin binding
MFIDAGO:0003700DNA-binding transcription factor activity
MFICGO:0003705transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
MFIDAGO:0003705transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
MFIBAGO:0003713transcription coactivator activity
MFIDAGO:0003713transcription coactivator activity
MFHDAGO:0003723RNA binding
MFIDAGO:0005096GTPase activator activity
MFIPIGO:0005515protein binding
MFIBAGO:0008134transcription factor binding
MFIPIGO:0008134transcription factor binding
MFIPIGO:0019899enzyme binding
MFIPIGO:0031625ubiquitin protein ligase binding
MFIDAGO:0035497cAMP response element binding
MFIPIGO:0042802identical protein binding
MFIDAGO:0042803protein homodimerization activity
MFIDAGO:0044212transcription regulatory region DNA binding
MFIDAGO:0046982protein heterodimerization activity
MFIPIGO:0070412R-SMAD binding
MFIEAGO:0071837HMG box domain binding
CCTASGO:0000228nuclear chromosome
CCIBAGO:0000790nuclear chromatin
CCIDAGO:0005634nucleus
CCIBAGO:0005654nucleoplasm
CCIDAGO:0005654nucleoplasm
CCTASGO:0005654nucleoplasm
CCIBAGO:0005667transcription factor complex
CCIDAGO:0005719nuclear euchromatin
CCIEAGO:0005829cytosol
CCIEAGO:0017053transcriptional repressor complex
CCIDAGO:0035976transcription factor AP-1 complex
CCIMPGO:0035976transcription factor AP-1 complex
BPIBAGO:0000122negative regulation of transcription by RNA polymerase II
BPIEAGO:0001525angiogenesis
BPIEAGO:0001774microglial cell activation
BPIEAGO:0001836release of cytochrome c from mitochondria
BPIEAGO:0001889liver development
BPIEAGO:0001938positive regulation of endothelial cell proliferation
BPIEAGO:0003151outflow tract morphogenesis
BPIEAGO:0006366transcription by RNA polymerase II
BPIDAGO:0007179transforming growth factor beta receptor signaling pathway
BPIDAGO:0007265Ras protein signal transduction
BPIEAGO:0007568aging
BPIEAGO:0007612learning
BPIEAGO:0007623circadian rhythm
BPIEAGO:0008285negative regulation of cell proliferation
BPIBAGO:0009314response to radiation
BPIBAGO:0009612response to mechanical stimulus
BPIBAGO:0010033response to organic substance
BPIEAGO:0010634positive regulation of epithelial cell migration
BPIBAGO:0010941regulation of cell death
BPIEAGO:0030224monocyte differentiation
BPIEAGO:0031103axon regeneration
BPIEAGO:0031953negative regulation of protein autophosphorylation
BPIBAGO:0032496response to lipopolysaccharide
BPIBAGO:0032870cellular response to hormone stimulus
BPIBAGO:0034097response to cytokine
BPIMPGO:0034614cellular response to reactive oxygen species
BPIEAGO:0035026leading edge cell differentiation
BPIEAGO:0035994response to muscle stretch
BPTASGO:0038095Fc-epsilon receptor signaling pathway
BPIBAGO:0042127regulation of cell proliferation
BPIBAGO:0042493response to drug
BPIEAGO:0042542response to hydrogen peroxide
BPIMPGO:0043065positive regulation of apoptotic process
BPIDAGO:0043392negative regulation of DNA binding
BPIEAGO:0043524negative regulation of neuron apoptotic process
BPIEAGO:0043525positive regulation of neuron apoptotic process
BPIEAGO:0043547positive regulation of GTPase activity
BPIDAGO:0043922negative regulation by host of viral transcription
BPIDAGO:0043923positive regulation by host of viral transcription
BPIBAGO:0045597positive regulation of cell differentiation
BPIEAGO:0045657positive regulation of monocyte differentiation
BPIEAGO:0045740positive regulation of DNA replication
BPIDAGO:0045892negative regulation of transcription, DNA-templated
BPIDAGO:0045893positive regulation of transcription, DNA-templated
BPIMPGO:0045893positive regulation of transcription, DNA-templated
BPIBAGO:0045944positive regulation of transcription by RNA polymerase II
BPICGO:0045944positive regulation of transcription by RNA polymerase II
BPIDAGO:0045944positive regulation of transcription by RNA polymerase II
BPIEAGO:0048146positive regulation of fibroblast proliferation
BPTASGO:0051090regulation of DNA-binding transcription factor activity
BPIEAGO:0051365cellular response to potassium ion starvation
BPIBAGO:0051591response to cAMP
BPIBAGO:0051726regulation of cell cycle
BPIEAGO:0051899membrane depolarization
BPIDAGO:0060395SMAD protein signal transduction
BPIEAGO:0061029eyelid development in camera-type eye
BPIEAGO:0070374positive regulation of ERK1 and ERK2 cascade
BPIMPGO:0071276cellular response to cadmium ion
BPIEAGO:0071277cellular response to calcium ion
BPIMPGO:1902895positive regulation of pri-miRNA transcription by RNA polymerase II
BPISSGO:1902895positive regulation of pri-miRNA transcription by RNA polymerase II
BPIMPGO:1904707positive regulation of vascular smooth muscle cell proliferation
BPIMPGO:1990441negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
BPIDAGO:2000144positive regulation of DNA-templated transcription, initiation

Gene expression in normal tissue: JUN

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in JUN


DatabasePathway IDPathway Des.
pidap1_pathwayAP-1 transcription factor network
pidar_tf_pathwayRegulation of Androgen receptor activity
pidatf2_pathwayATF-2 transcription factor network
pidavb3_opn_pathwayOsteopontin-mediated events
pidbcr_5pathwayBCR signaling pathway
pidbetacatenin_nuc_pathwayRegulation of nuclear beta catenin signaling and target gene transcription
pidcd40_pathwayCD40/CD40L signaling
pidcd8tcrdownstreampathwayDownstream signaling in naïve CD8+ T cells
pidcdc42_pathwayCDC42 signaling events
pidendothelinpathwayEndothelins
pidera_genomic_pathwayValidated nuclear estrogen receptor alpha network
piderbb1_downstream_pathwayErbB1 downstream signaling
piderbb2erbb3pathwayErbB2/ErbB3 signaling events
pidfak_pathwaySignaling events mediated by focal adhesion kinase
pidfcer1pathwayFc-epsilon receptor I signaling in mast cells
pidfgf_pathwayFGF signaling pathway
pidfra_pathwayValidated transcriptional targets of AP1 family members Fra1 and Fra2
pidhif1_tfpathwayHIF-1-alpha transcription factor network
pidhnf3apathwayFOXA1 transcription factor network
pidil12_stat4pathwayIL12 signaling mediated by STAT4
pidil1pathwayIL1-mediated signaling events
pidil2_1pathwayIL2-mediated signaling events
pidil6_7pathwayIL6-mediated signaling events
pidilk_pathwayIntegrin-linked kinase signaling
pidlysophospholipid_pathwayLPA receptor mediated events
pidmet_pathwaySignaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
pidnephrin_neph1_pathwayNephrin/Neph1 signaling in the kidney podocyte
pidnfat_tfpathwayCalcineurin-regulated NFAT-dependent transcription in lymphocytes
pidp38alphabetadownstreampathwaySignaling mediated by p38-alpha and p38-beta
pidp53downstreampathwayDirect p53 effectors
pidpdgfrapathwayPDGFR-alpha signaling pathway
pidpdgfrbpathwayPDGFR-beta signaling pathway
pidps1pathwayPresenilin action in Notch and Wnt signaling
pidrac1_pathwayRAC1 signaling pathway
pidrb_1pathwayRegulation of retinoblastoma protein
pidreg_gr_pathwayGlucocorticoid receptor regulatory network
pidret_pathwaySignaling events regulated by Ret tyrosine kinase
pidrhoa_pathwayRhoA signaling pathway
pids1p_s1p2_pathwayS1P2 pathway
pidsmad2_3nuclearpathwayRegulation of nuclear SMAD2/3 signaling
pidtcrcalciumpathwayCalcium signaling in the CD4+ TCR pathway
pidtcrjnkpathwayJNK signaling in the CD4+ TCR pathway
pidtelomerasepathwayRegulation of Telomerase
pharmgkbPA162356267EGFR Inhibitor Pathway, Pharmacodynamics
pharmgkbPA165980050Vemurafenib Pathway, Pharmacodynamics
pharmgkbPA165980050update your name in edit mode
pharmgkbPA165985892Tacrolimus/Cyclosporine Pathway, Pharmacodynamics
smpdbSMP00320Intracellular Signalling Through Adenosine Receptor A2a and Adenosine
smpdbSMP00321Intracellular Signalling Through Adenosine Receptor A2b and Adenosine
wikipathwaysWP127IL-5 Signaling Pathway
wikipathwaysWP138Androgen receptor signaling pathway
wikipathwaysWP1449Regulation of toll-like receptor signaling pathway
wikipathwaysWP1528Physiological and Pathological Hypertrophy of the Heart
wikipathwaysWP1772Apoptosis Modulation and Signaling
wikipathwaysWP195IL-1 signaling pathway
wikipathwaysWP1984Integrated Breast Cancer Pathway
wikipathwaysWP2018RANKL-RANK (Receptor activator of NFKB (ligand)) Signaling Pathway
wikipathwaysWP2032Human Thyroid Stimulating Hormone (TSH) signaling pathway
wikipathwaysWP2036TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway
wikipathwaysWP2037Prolactin Signaling Pathway
wikipathwaysWP2263Androgen Receptor Network in Prostate Cancer
wikipathwaysWP23B Cell Receptor Signaling Pathway
wikipathwaysWP231TNF alpha Signaling Pathway
wikipathwaysWP2324AGE-RAGE pathway
wikipathwaysWP2380Brain-Derived Neurotrophic Factor (BDNF) signaling pathway
wikipathwaysWP2435Quercetin and Nf-kB- AP-1 Induced Cell Apoptosis
wikipathwaysWP2512Integrated Lung Cancer Pathway
wikipathwaysWP2516ATM Signaling Pathway
wikipathwaysWP254Apoptosis
wikipathwaysWP2571Polycystic Kidney Disease Pathway
wikipathwaysWP2593JAK-STAT
wikipathwaysWP28Selenium Metabolism and Selenoproteins
wikipathwaysWP286IL-3 Signaling Pathway
wikipathwaysWP2873Aryl Hydrocarbon Receptor Pathway
wikipathwaysWP2880Glucocorticoid Receptor Pathway
wikipathwaysWP2881Estrogen Receptor Pathway
wikipathwaysWP2882Nuclear Receptors Meta-Pathway
wikipathwaysWP289Myometrial Relaxation and Contraction Pathways
wikipathwaysWP306Focal Adhesion
wikipathwaysWP313Signaling of Hepatocyte Growth Factor Receptor
wikipathwaysWP314Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation
wikipathwaysWP3286Copper homeostasis
wikipathwaysWP3301MFAP5-mediated ovarian cancer cell motility and invasiveness
wikipathwaysWP3611Photodynamic therapy-induced AP-1 survival signaling.
wikipathwaysWP3612Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling
wikipathwaysWP3639Apoptotic Signaling Pathway
wikipathwaysWP3646Hepatitis C and Hepatocellular Carcinoma
wikipathwaysWP366TGF-beta Signaling Pathway
wikipathwaysWP3680Association Between Physico-Chemical Features and Toxicity Associated Pathways
wikipathwaysWP382MAPK Signaling Pathway
wikipathwaysWP3863T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection
wikipathwaysWP3888VEGFA-VEGFR2 Signaling Pathway
wikipathwaysWP3927BMP Signaling Pathway in Eyelid Development
wikipathwaysWP3931ESC Pluripotency Pathways
wikipathwaysWP3972PDGFR-beta pathway
wikipathwaysWP399Wnt Signaling Pathway and Pluripotency
wikipathwaysWP4205MET in type 1 papillary renal cell carcinoma
wikipathwaysWP4216Chromosomal and microsatellite instability in colorectal cancer
wikipathwaysWP422MAPK Cascade
wikipathwaysWP428Wnt Signaling Pathway
wikipathwaysWP437EGF-EGFR Signaling Pathway
wikipathwaysWP481Insulin Signaling
wikipathwaysWP49IL-2 Signaling Pathway
wikipathwaysWP560TGF-beta Receptor Signaling
wikipathwaysWP615Senescence and Autophagy in Cancer
wikipathwaysWP673ErbB Signaling Pathway
wikipathwaysWP69T-Cell antigen Receptor (TCR) Signaling Pathway
wikipathwaysWP706Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways
wikipathwaysWP710DNA Damage Response (only ATM dependent)
wikipathwaysWP712Estrogen signaling pathway
wikipathwaysWP75Toll-like Receptor Signaling Pathway
kegghsa04010MAPK signaling pathway - Homo sapiens (human)
kegghsa04012ErbB signaling pathway - Homo sapiens (human)
kegghsa04024cAMP signaling pathway - Homo sapiens (human)
kegghsa04137Mitophagy - animal - Homo sapiens (human)
kegghsa04210Apoptosis - Homo sapiens (human)
kegghsa04310Wnt signaling pathway - Homo sapiens (human)
kegghsa04380Osteoclast differentiation - Homo sapiens (human)
kegghsa04510Focal adhesion - Homo sapiens (human)
kegghsa04530Tight junction - Homo sapiens (human)
kegghsa04620Toll-like receptor signaling pathway - Homo sapiens (human)
kegghsa04621NOD-like receptor signaling pathway - Homo sapiens (human)
kegghsa04625C-type lectin receptor signaling pathway - Homo sapiens (human)
kegghsa04657IL-17 signaling pathway - Homo sapiens (human)
kegghsa04658Th1 and Th2 cell differentiation - Homo sapiens (human)
kegghsa04659Th17 cell differentiation - Homo sapiens (human)
kegghsa04660T cell receptor signaling pathway - Homo sapiens (human)
kegghsa04662B cell receptor signaling pathway - Homo sapiens (human)
kegghsa04668TNF signaling pathway - Homo sapiens (human)
kegghsa04722Neurotrophin signaling pathway - Homo sapiens (human)
kegghsa04912GnRH signaling pathway - Homo sapiens (human)
kegghsa04915Estrogen signaling pathway - Homo sapiens (human)
kegghsa04921Oxytocin signaling pathway - Homo sapiens (human)
kegghsa04926Relaxin signaling pathway - Homo sapiens (human)
kegghsa04932Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human)
kegghsa04933AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)
kegghsa05030Cocaine addiction - Homo sapiens (human)
kegghsa05031Amphetamine addiction - Homo sapiens (human)
kegghsa05120Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human)
kegghsa05132Salmonella infection - Homo sapiens (human)
kegghsa05133Pertussis - Homo sapiens (human)
kegghsa05140Leishmaniasis - Homo sapiens (human)
kegghsa05142Chagas disease (American trypanosomiasis) - Homo sapiens (human)
kegghsa05161Hepatitis B - Homo sapiens (human)
kegghsa05164Influenza A - Homo sapiens (human)
kegghsa05166HTLV-I infection - Homo sapiens (human)
kegghsa05167Kaposi,s sarcoma-associated herpesvirus infection - Homo sapiens (human)
kegghsa05168Herpes simplex infection - Homo sapiens (human)
kegghsa05169Epstein-Barr virus infection - Homo sapiens (human)
kegghsa05200Pathways in cancer - Homo sapiens (human)
kegghsa05203Viral carcinogenesis - Homo sapiens (human)
kegghsa05210Colorectal cancer - Homo sapiens (human)
kegghsa05211Renal cell carcinoma - Homo sapiens (human)
kegghsa05224Breast cancer - Homo sapiens (human)
kegghsa05231Choline metabolism in cancer - Homo sapiens (human)
kegghsa05321Inflammatory bowel disease (IBD) - Homo sapiens (human)
kegghsa05323Rheumatoid arthritis - Homo sapiens (human)
kegghsa05418Fluid shear stress and atherosclerosis - Homo sapiens (human)
netpathPathway_Alpha6Beta4IntegrinAlpha6Beta4Integrin
netpathPathway_AndrogenReceptorAndrogenReceptor
netpathPathway_BCRBCR
netpathPathway_EGFR1EGFR1
netpathPathway_GastrinGastrin
netpathPathway_IL1IL1
netpathPathway_IL2IL2
netpathPathway_IL5IL5
netpathPathway_IL6IL6
netpathPathway_KitReceptorKitReceptor
netpathPathway_ProlactinProlactin
netpathPathway_RAGERAGE
netpathPathway_TGF_beta_ReceptorTGF_beta_Receptor
netpathPathway_TNFalphaTNFalpha
netpathPathway_WntWnt
reactomeR-HSA-1257604PIP3 activates AKT signaling
reactomeR-HSA-1257604PIP3 activates AKT signaling
reactomeR-HSA-1266738Developmental Biology
reactomeR-HSA-1280215Cytokine Signaling in Immune system
reactomeR-HSA-157118Signaling by NOTCH
reactomeR-HSA-162582Signal Transduction
reactomeR-HSA-162582Signal Transduction
reactomeR-HSA-1643685Disease
reactomeR-HSA-166016Toll Like Receptor 4 (TLR4) Cascade
reactomeR-HSA-166058MyD88:Mal cascade initiated on plasma membrane
reactomeR-HSA-166166MyD88-independent TLR4 cascade
reactomeR-HSA-168138Toll Like Receptor 9 (TLR9) Cascade
reactomeR-HSA-168142Toll Like Receptor 10 (TLR10) Cascade
reactomeR-HSA-168164Toll Like Receptor 3 (TLR3) Cascade
reactomeR-HSA-168176Toll Like Receptor 5 (TLR5) Cascade
reactomeR-HSA-168179Toll Like Receptor TLR1:TLR2 Cascade
reactomeR-HSA-168181Toll Like Receptor 7/8 (TLR7/8) Cascade
reactomeR-HSA-168188Toll Like Receptor TLR6:TLR2 Cascade
reactomeR-HSA-168249Innate Immune System
reactomeR-HSA-168256Immune System
reactomeR-HSA-168898Toll-Like Receptors Cascades
reactomeR-HSA-181438Toll Like Receptor 2 (TLR2) Cascade
reactomeR-HSA-1912408Pre-NOTCH Transcription and Translation
reactomeR-HSA-1912422Pre-NOTCH Expression and Processing
reactomeR-HSA-212436Generic Transcription Pathway
reactomeR-HSA-2262752Cellular responses to stress
reactomeR-HSA-2454202Fc epsilon receptor (FCERI) signaling
reactomeR-HSA-2559580Oxidative Stress Induced Senescence
reactomeR-HSA-2559582Senescence-Associated Secretory Phenotype (SASP)
reactomeR-HSA-2559583Cellular Senescence
reactomeR-HSA-2871796FCERI mediated MAPK activation
reactomeR-HSA-3700989Transcriptional Regulation by TP53
reactomeR-HSA-448424Interleukin-17 signaling
reactomeR-HSA-449147Signaling by Interleukins
reactomeR-HSA-450282MAPK targets/ Nuclear events mediated by MAP kinases
reactomeR-HSA-450294MAP kinase activation
reactomeR-HSA-450341Activation of the AP-1 family of transcription factors
reactomeR-HSA-5617472Activation of anterior HOX genes in hindbrain development during early embryogenesis
reactomeR-HSA-5619507Activation of HOX genes during differentiation
reactomeR-HSA-5683057MAPK family signaling cascades
reactomeR-HSA-5687128MAPK6/MAPK4 signaling
reactomeR-HSA-6796648TP53 Regulates Transcription of DNA Repair Genes
reactomeR-HSA-6807070PTEN Regulation
reactomeR-HSA-6807070PTEN Regulation
reactomeR-HSA-73857RNA Polymerase II Transcription
reactomeR-HSA-74160Gene expression (Transcription)
reactomeR-HSA-8862803Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
reactomeR-HSA-8863678Neurodegenerative Diseases
reactomeR-HSA-8939211ESR-mediated signaling
reactomeR-HSA-8943724Regulation of PTEN gene transcription
reactomeR-HSA-8943724Regulation of PTEN gene transcription
reactomeR-HSA-8953897Cellular responses to external stimuli
reactomeR-HSA-9006925Intracellular signaling by second messengers
reactomeR-HSA-9006925Intracellular signaling by second messengers
reactomeR-HSA-9006931Signaling by Nuclear Receptors
reactomeR-HSA-9018519Estrogen-dependent gene expression
reactomeR-HSA-937061TRIF(TICAM1)-mediated TLR4 signaling
reactomeR-HSA-975138TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
reactomeR-HSA-975155MyD88 dependent cascade initiated on endosome
reactomeR-HSA-975871MyD88 cascade initiated on plasma membrane
biocarta41bbpathwaythe 41bb-dependent immune response
biocartaagrpathwayagrin in postsynaptic differentiation
biocartaarenrf2pathwayoxidative stress induced gene expression via nrf2
biocartaat1rpathwayangiotensin ii mediated activation of jnk pathway via pyk2 dependent signaling
biocartaatmpathwayatm signaling pathway
biocartabcrpathwaybcr signaling pathway
biocartacardiacegfpathwayrole of egf receptor transactivation by gpcrs in cardiac hypertrophy
biocartaccr5pathwaypertussis toxin-insensitive ccr5 signaling in macrophage
biocartacdmacpathwaycadmium induces dna synthesis and proliferation in macrophages
biocartad4gdipathwayd4gdi signaling pathway
biocartadreampathwayrepression of pain sensation by the transcriptional regulator dream
biocartaeponfkbpathwayerythropoietin mediated neuroprotection through nf-kb
biocartaetspathwaymets affect on macrophage differentiation
biocartafcer1pathwayfc epsilon receptor i signaling in mast cells
biocartagleevecpathwayinhibition of cellular proliferation by gleevec
biocartahbxpathwaycalcium signaling by hbx of hepatitis b virus
biocartahifpathwayhypoxia-inducible factor in the cardivascular system
biocartaigf1pathwayigf-1 signaling pathway
biocartail12pathwayil12 and stat4 dependent signaling pathway in th1 development
biocartail1rpathwaysignal transduction through il1r
biocartakeratinocytepathwaykeratinocyte differentiation
biocartamapkpathwaymapkinase signaling pathway
biocartangfpathwaynerve growth factor pathway (ngf)
biocartapcafpathwaythe information processing pathway at the ifn beta enhancer
biocartapdgfpathwaypdgf signaling pathway
biocartapparapathwaymechanism of gene regulation by peroxisome proliferators via ppara
biocartapyk2pathwaylinks between pyk2 and map kinases
biocartastresspathwaytnf/stress related signaling
biocartatcrpathwayt cell receptor signaling pathway
biocartatollpathwaytoll-like receptor pathway
biocartatpopathwaytpo signaling pathway
biocartatsp1pathwaytsp-1 induced apoptosis in microvascular endothelial cell

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD885Compound 1101
iGMDRD289Parthenolide2
iGMDRD284Palbociclib1
iGMDRD424Tamatinib2
iGMDRD512nutlin 31
iGMDRD137Indisulam6
iGMDRD158NSC1415401
iGMDRD25138402-11-61
iGMDRD147Prima-11
iGMDRD394BX-7952
iGMDRD398Sepantronium3

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in JUN

​​​​