iGMDRD602

Canonical SMILES: COC1=CC2=C(C=CN=C2C=C1OCCCN3CCOCC3)OC4=C(C=C(C=C4)NC(=O)C5(CC5)C(=O)NC6=CC=C(C=C6)F)F

InChI: InChI=1S/C34H34F2N4O6/c1-43-30-20-25-27(21-31(30)45-16-2-13-40-14-17-44-18-15-40)37-12-9-28(25)46-29-8-7-24(19-26(29)36)39-33(42)34(10-11-34)32(41)38-23-5-3-22(35)4-6-23/h3-9,12,19-21H,2,10-11,13-18H2,1H3,(H,38,41)(H,39,42)

InChI Key: CXQHYVUVSFXTMY-UHFFFAOYSA-N

Standard NameCHEMBLPubchem CIDDRUGBANK IDDrug StatusDrug Type
ForetinibCHEMBL1230609 42642600DB12307AloneSmall Molecule


Drug Pathways:

RTK signaling

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
7514XPO12
2956MSH61
4170MCL11
5175PECAM11
5159PDGFRB1
4851NOTCH11
92ACVR2A1
6098ROS15
1029CDKN2A1
7157TP531
8923202COX21
5727PTCH12
7270TTF11
8731RNMT1
2067ERCC11
100862685ERVK-191
4893NRAS2
25ABL11

Gene in drug-gene network: Network Plot

Models in Foretinib

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