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iGMDRD33

Canonical SMILES: C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC(=O)OCC3=CN=CC=C3

InChI: InChI=1S/C21H20N4O3/c22-18-5-1-2-6-19(18)25-20(26)17-9-7-15(8-10-17)13-24-21(27)28-14-16-4-3-11-23-12-16/h1-12H,13-14,22H2,(H,24,27)(H,25,26)

InChI Key: INVTYAOGFAGBOE-UHFFFAOYSA-N

Standard Name	CHEMBL	Pubchem CID	DRUGBANK ID	Drug Status	Drug Type
Entinostat	CHEMBL27759 CHEMBL3093129	4261	DB11841	Alone	Small Molecule

Drug Class:

Acids, Carbocyclic Amides Antineoplastic Agents Benzene Derivatives Benzoates Carboxylic Acids Enzyme Inhibitors Heterocyclic Compounds Heterocyclic Compounds, 1-Ring Histone Deacetylase Inhibitors Hydrocarbons Hydrocarbons, Aromatic Hydrocarbons, Cyclic

Drug Targets:

HDAC

Drug Pathways:

Chromatin histone acetylation

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Gene ID	Gene Name	Model Num.
6597	SMARCA4	1
9757	KMT2B	1
55294	FBXW7	1
637	BID	1
597	BCL2A1	2
7037	TFRC	1
6850	SYK	1
10413	YAP1	1
3932	LCK	1
7157	TP53	1
3673	ITGA2	1
6714	SRC	1
6794	STK11	1
4292	MLH1	1
2133	EXT3	1
162979	ZNF296	2
4089	SMAD4	1
1956	EGFR	1
11315	PARK7	1
5054	SERPINE1	1
5925	RB1	1
2065	ERBB3	1

Gene in drug-gene network: Network Plot

Models in Entinostat

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DATATYPES

CLASSFICATION

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.