iGMDRD472

Canonical SMILES: CN(C1=C(C=CC=N1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)C4)S(=O)(=O)C

InChI: InChI=1S/C21H20F3N7O3S/c1-31(35(2,33)34)19-12(4-3-7-25-19)10-26-18-15(21(22,23)24)11-27-20(30-18)28-14-5-6-16-13(8-14)9-17(32)29-16/h3-8,11H,9-10H2,1-2H3,(H,29,32)(H2,26,27,28,30)

InChI Key: MZDKLVOWGIOKTN-UHFFFAOYSA-N

Standard NameCHEMBLPubchem CIDDrug StatusDrug Type
PF-562271CHEMBL1084546 CHEMBL2430359 11713200AloneSmall Molecule

Drug Targets:

FAKFAK2

Drug Pathways:

Cytoskeleton

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
3845KRAS2
6657SOX21
55294FBXW71
25937WWTR11
6850SYK1
3673ITGA21
2322FLT31
3791KDR1
4089SMAD41
5290PIK3CA1
1956EGFR1
673BRAF2
100862685ERVK-191
5054SERPINE11
196528ARID21
4893NRAS1
7403KDM6A1
4780NFE2L21

Gene in drug-gene network: Network Plot

Models in PF-562271

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