iGMDRD593


Canonical SMILES: CC1=CN=C(C=N1)CNC(=O)C2=C3N(C4=CC=CC=C4S3)C5=C(C2=O)C=CC(=N5)N6CCCN(CC6)C

InChI: InChI=1S/C27H27N7O2S/c1-17-14-29-18(15-28-17)16-30-26(36)23-24(35)19-8-9-22(33-11-5-10-32(2)12-13-33)31-25(19)34-20-6-3-4-7-21(20)37-27(23)34/h3-4,6-9,14-15H,5,10-13,16H2,1-2H3,(H,30,36)

InChI Key: XGPBJCHFROADCK-UHFFFAOYSA-N

Standard NamePubchem CIDDrug StatusDrug Type
CX-546125257600AloneSmall Molecule

Drug Targets:

RNA Pol I

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
3845KRAS1
8289ARID1A1
6597SMARCA41
4771NF22
9757KMT2B4
2033EP3001
54464XRN11
23239PHLPP11
1029CDKN2A3
7157TP531
3105HLA-A1
8731RNMT1
4609MYC1
3553IL1B1
7027TFDP11
171023ASXL12
4893NRAS1
7040TGFB12
4763NF11
4613MYCN1
2146EZH21

Gene in drug-gene network: Network Plot

Models in CX-5461

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