HOXC13


Summary: This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene may play a role in the development of hair, nail, and filiform papilla. [provided by RefSeq, Jul 2008].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
OMIM IDMIM:142976
PHARMGKB IDPA29400
Map Location12q13.13

GO terms in HOXC13


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Term Type
Evidence Type
GO Term ID
GO Des.
MF ISA GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding
MF ISM GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding
MF NAS GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding
MF IEA GO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
MF IEA GO:0003682 chromatin binding
MF IPI GO:0005515 protein binding
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Gene expression in normal tissue: HOXC13

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in HOXC13


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD366 PI-103 1
iGMDRD562 Navitoclax 6
iGMDRD577 BIX01294 3
iGMDRD74 Idarubicin 3
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in HOXC13

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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