iGMDRD3

Canonical SMILES: CCN(CC)CCCCNC1=NC2=NC(=C(C=C2C=N1)C3=CC(=CC(=C3)OC)OC)NC(=O)NC(C)(C)C

InChI: InChI=1S/C28H41N7O3/c1-8-35(9-2)13-11-10-12-29-26-30-18-20-16-23(19-14-21(37-6)17-22(15-19)38-7)25(31-24(20)32-26)33-27(36)34-28(3,4)5/h14-18H,8-13H2,1-7H3,(H3,29,30,31,32,33,34,36)

InChI Key: DXCUKNQANPLTEJ-UHFFFAOYSA-N

Standard NameCHEMBLPubchem CIDDrug StatusDrug Type
PD-173074CHEMBL189584 1401AloneSmall Molecule

Drug Targets:

FGFR1FGFR3

Drug Pathways:

RTK signaling

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
3845KRAS1
57580PREX11
6598SMARCB11
9757KMT2B1
1387CREBBP1
2260FGFR14
3106HLA-B1
6850SYK1
861RUNX11
7157TP532
2322FLT31
4292MLH11
2263FGFR23
57111RAB251
2186BPTF1
5156PDGFRA1
673BRAF1
5728PTEN1
4893NRAS1
7403KDM6A1
2261FGFR31

Gene in drug-gene network: Network Plot

Models in PD-173074

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