USP6
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| ubiquitin specific peptidase 6 | MIM:604334 | Ensembl:ENSG00000129204 | HGNC:HGNC:12629 | PA37254 | 17p13.2 |
GO terms in USP6
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IDA | GO:0005737 | cytoplasm |
| CC | TAS | GO:0005764 | lysosome |
| CC | IDA | GO:0005886 | plasma membrane |
| CC | IDA | GO:0055037 | recycling endosome |
| BP | NAS | GO:0006464 | cellular protein modification process |
| BP | IEA | GO:0006511 | ubiquitin-dependent protein catabolic process |
| BP | IBA | GO:0006886 | intracellular protein transport |
| BP | IDA | GO:0016579 | protein deubiquitination |
| BP | IDA | GO:0060627 | regulation of vesicle-mediated transport |
| BP | IBA | GO:0090630 | activation of GTPase activity |
| MF | TAS | GO:0003676 | nucleic acid binding |
| MF | TAS | GO:0004197 | cysteine-type endopeptidase activity |
| MF | IDA | GO:0004843 | thiol-dependent ubiquitin-specific protease activity |
| MF | IBA | GO:0005096 | GTPase activator activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IEA | GO:0005516 | calmodulin binding |
| MF | IBA | GO:0017137 | Rab GTPase binding |
Gene expression in normal tissue: USP6
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD560 | MK-2206 | 1 |
| iGMDRD427 | ABT737 | 2 |
| iGMDRD781 | Sirolimus | 4 |
| iGMDRD126 | Tipifarnib | 2 |
| iGMDRD387 | CHIR-99021 | 2 |
| iGMDRD123 | Isoevodiamine | 2 |
| iGMDRD341 | Triacsin c | 9 |
| iGMDRD237 | ABT-751 | 2 |
| iGMDRD61 | Kinetin riboside | 7 |
| iGMDRD6 | AM-580 | 4 |
| iGMDRD434 | BMS-536924 | 3 |
| iGMDRD481 | Dactolisib | 2 |
| iGMDRD733 | SGC0946 | 1 |
| iGMDRD187 | BRD9876 | 2 |
| iGMDRD474 | Avrainvillamide | 2 |
| iGMDRD158 | NSC141540 | 2 |
| iGMDRD369 | TGX-115 | 2 |
| iGMDRD64 | Parbendazole | 1 |
| iGMDRD60 | Quinoclamine | 2 |
| iGMDRD100 | Zebularine | 1 |
| iGMDRD67 | PENFLURIDOL | 3 |
| iGMDRD188 | Piperlongumine | 2 |
| iGMDRD399 | Selumetinib | 2 |
| iGMDRD577 | BIX01294 | 2 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in USP6
CLASSFICATION
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