iGMDRD489

Canonical SMILES: CC(C1=CC=CC=C1C(F)(F)F)OC2=C(SC(=C2)N3C=NC4=C3C=C(C=C4)CN5CCN(CC5)C)C(=O)N

InChI: InChI=1S/C27H28F3N5O2S/c1-17(19-5-3-4-6-20(19)27(28,29)30)37-23-14-24(38-25(23)26(31)36)35-16-32-21-8-7-18(13-22(21)35)15-34-11-9-33(2)10-12-34/h3-8,13-14,16-17H,9-12,15H2,1-2H3,(H2,31,36)/t17-/m1/s1

InChI Key: ZHJGWYRLJUCMRT-QGZVFWFLSA-N

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Standard Name
CHEMBL
Pubchem CID
Drug Status
Drug Type
Standard NameGSK-461364
CHEMBLCHEMBL1908394
Pubchem CID15984000
Drug StatusAlone
Drug TypeSmall Molecule

Drug Targets:

PLK1

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
7514 XPO1 2
10987 COPS5 1
2956 MSH6 1
4170 MCL1 1
Showing 1 to 4 of 23 rows rows per page

Gene in drug-gene network: Network Plot

Models in GSK-461364

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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