iGMDRD63

Canonical SMILES: CCC1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)O

InChI: InChI=1S/C20H16N2O4/c1-2-20(25)14-8-16-17-12(7-11-5-3-4-6-15(11)21-17)9-22(16)18(23)13(14)10-26-19(20)24/h3-8,25H,2,9-10H2,1H3/t20-/m0/s1

InChI Key: VSJKWCGYPAHWDS-FQEVSTJZSA-N

Standard NameCHEMBLPubchem CIDDRUGBANK IDDrug StatusDrug Type
CamptothecinCHEMBL65 24360DB04690AloneSmall Molecule


Drug Targets:

TOP1 (P11387)

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
7514XPO11
103ADAR1
3845KRAS1
4172MCM31
9757KMT2B1
7158TP53BP11
1846DUSP41
25937WWTR11
2064ERBB22
1029CDKN2A2
2309FOXO31
57111RAB251
6391SDHC1
4609MYC2
1938EEF21
2113ETS11
8651SOCS11
2648KAT2A2
171023ASXL11
8821INPP4B2
2067ERCC11
9223MAGI11
9402GRAP21
1660DHX91
5624PROC1

Gene in drug-gene network: Network Plot

Models in Camptothecin

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