TFEB


Summary:

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
transcription factor EBMIM:600744Ensembl:ENSG00000112561HGNC:HGNC:11753PA364686p21.1

GO terms in TFEB


Term TypeEvidence TypeGO Term IDGO Des.
MFISAGO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding
MFISMGO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding
MFNASGO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding
MFIDAGO:0003700DNA-binding transcription factor activity
MFNASGO:0003700DNA-binding transcription factor activity
MFIDAGO:0044212transcription regulatory region DNA binding
MFIEAGO:0046983protein dimerization activity
CCIDAGO:0005634nucleus
CCNASGO:0005634nucleus
CCIDAGO:0005737cytoplasm
BPISSGO:0001892embryonic placenta development
BPIEAGO:0002250adaptive immune response
BPIEAGO:0006351transcription, DNA-templated
BPNASGO:0006355regulation of transcription, DNA-templated
BPIEAGO:0006914autophagy
BPISSGO:0006959humoral immune response
BPIMPGO:0007040lysosome organization
BPIMPGO:0010508positive regulation of autophagy
BPIDAGO:0045944positive regulation of transcription by RNA polymerase II

Gene expression in normal tissue: TFEB

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in TFEB


DatabasePathway IDPathway Des.
kegghsa04137Mitophagy - animal - Homo sapiens (human)
wikipathwaysWP3844PI3K-AKT-mTOR signaling pathway and therapeutic opportunities
wikipathwaysWP4241Type 2 papillary renal cell carcinoma

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD289Parthenolide3
iGMDRD481Dactolisib3
iGMDRD121GMX17783
iGMDRD474Avrainvillamide2
iGMDRD103SN-383
iGMDRD147Prima-13
iGMDRD505Pevonedistat1
iGMDRD322FK 8661
iGMDRD188Piperlongumine1
iGMDRD562Navitoclax3
iGMDRD427ABT7373
iGMDRD144NSC953973
iGMDRD701NVP-AUY9222
iGMDRD126Tipifarnib7
iGMDRD466Chaetocin3
iGMDRD123Isoevodiamine3
iGMDRD394BX-7951
iGMDRD85Ursolic acid1
iGMDRD351GW843682X3

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in TFEB

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