iGMDRD313
Canonical SMILES: CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=NN3)C=CC4=CC=CC=N4
InChI: InChI=1S/C22H18N4OS/c1-23-22(27)18-7-2-3-8-21(18)28-16-10-11-17-19(25-26-20(17)14-16)12-9-15-6-4-5-13-24-15/h2-14H,1H3,(H,23,27)(H,25,26)/b12-9+
InChI Key: RITAVMQDGBJQJZ-FMIVXFBMSA-N
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Standard Name | CHEMBL | Pubchem CID | DRUGBANK ID | Drug Status | Drug Type |
|---|---|---|---|---|---|
Standard NameAxitinib CHEMBLCHEMBL1289926 Pubchem CID6450550 DRUGBANK IDDB06626 Drug StatusAlone Drug TypeSmall Molecule | |||||
Drug Class:
Antineoplastic AgentsAntineoplastic and Immunomodulating AgentsAzolesCytochrome P-450 CYP1A2 SubstratesEnzyme InhibitorsHeterocyclic CompoundsHeterocyclic Compounds, 1-RingHeterocyclic Compounds, 2-RingKinase InhibitorOATP1B1/SLCO1B1 SubstratesP-glycoprotein/ABCB1 SubstratesProtein Kinase InhibitorsPyrazolesUGT1A1 SubstratesDrug Pathways:
RTK signalingDrug-model tissue-cancer distribution: Bubble Plot
Drug-gene pathway enrichments
Drug-gene GO enrichments
Drug-Gene: Aster Plot
Gene in drug-gene network: Network Plot
Models in Axitinib
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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