GO terms in NLK


Term TypeEvidence TypeGO Term IDGO Des.
BPIEAGO:0000165MAPK cascade
BPIEAGO:0006351transcription, DNA-templated
BPISSGO:0006355regulation of transcription, DNA-templated
BPISSGO:0006468protein phosphorylation
BPIMPGO:0007179transforming growth factor beta receptor signaling pathway
BPTASGO:0007223Wnt signaling pathway, calcium modulating pathway
BPIBAGO:0010468regulation of gene expression
BPISSGO:0018107peptidyl-threonine phosphorylation
BPISSGO:0030178negative regulation of Wnt signaling pathway
BPIBAGO:0035556intracellular signal transduction
BPISSGO:0035556intracellular signal transduction
BPISSGO:0042501serine phosphorylation of STAT protein
BPIEAGO:0046777protein autophosphorylation
BPIDAGO:0050821protein stabilization
CCIBAGO:0005634nucleus
CCISSGO:0005634nucleus
CCTASGO:0005654nucleoplasm
CCIBAGO:0005737cytoplasm
CCTASGO:0005829cytosol
MFISSGO:0000287magnesium ion binding
MFTASGO:0004672protein kinase activity
MFTASGO:0004674protein serine/threonine kinase activity
MFISSGO:0004707MAP kinase activity
MFIPIGO:0005515protein binding
MFISSGO:0005524ATP binding
MFIPIGO:0008134transcription factor binding
MFIPIGO:0031625ubiquitin protein ligase binding
MFISSGO:0042169SH2 domain binding

Gene expression in normal tissue: NLK

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in NLK


DatabasePathway IDPathway Des.
pidcmyb_pathwayC-MYB transcription factor network
pidps1pathwayPresenilin action in Notch and Wnt signaling
pidwnt_noncanonical_pathwayNoncanonical Wnt signaling pathway
kegghsa04010MAPK signaling pathway - Homo sapiens (human)
kegghsa04068FoxO signaling pathway - Homo sapiens (human)
kegghsa04310Wnt signaling pathway - Homo sapiens (human)
kegghsa04520Adherens junction - Homo sapiens (human)
netpathPathway_IL6IL6
netpathPathway_WntWnt
wikipathwaysWP2857Mesodermal Commitment Pathway
wikipathwaysWP2858Ectoderm Differentiation
wikipathwaysWP363Wnt Signaling Pathway
wikipathwaysWP364IL-6 signaling pathway
wikipathwaysWP382MAPK Signaling Pathway
wikipathwaysWP399Wnt Signaling Pathway and Pluripotency
wikipathwaysWP428Wnt Signaling Pathway
reactomeR-HSA-162582Signal Transduction
reactomeR-HSA-195721Signaling by WNT
reactomeR-HSA-3858494Beta-catenin independent WNT signaling
reactomeR-HSA-4086398Ca2+ pathway
biocartawntpathwaywnt signaling pathway

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD512nutlin 32
iGMDRD126Tipifarnib1
iGMDRD210AC556491
iGMDRD781Sirolimus2
iGMDRD427ABT7373
iGMDRD351GW843682X4
iGMDRD57Chloropentafluorobenzene2
iGMDRD152179324-69-74
iGMDRD945ML2143
iGMDRD154NSC237661
iGMDRD211(1S,3R)-RSL32
iGMDRD280CYTOCHALASIN B3
iGMDRD123Isoevodiamine2
iGMDRD138PX 122
iGMDRD705Nakiterpiosin2
iGMDRD105Triptolide2
iGMDRD171Pemetrexed2
iGMDRD577BIX012945
iGMDRD329Merck602
iGMDRD398Sepantronium3
iGMDRD366PI-1032
iGMDRD100Zebularine2
iGMDRD887Compound 23 citrate1
iGMDRD451Serdemetan3

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in NLK

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