GO terms in TNRC6B


Term TypeEvidence TypeGO Term IDGO Des.
CCIEAGO:0000932P-body
CCTASGO:0005829cytosol
BPTASGO:0007223Wnt signaling pathway, calcium modulating pathway
BPIMPGO:0031047gene silencing by RNA
BPTASGO:0035194posttranscriptional gene silencing by RNA
BPIEAGO:0035278miRNA mediated inhibition of translation
BPTASGO:0045652regulation of megakaryocyte differentiation
BPIMPGO:0060213positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
BPIMPGO:1900153positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
MFHDAGO:0003723RNA binding
MFIPIGO:0005515protein binding

Gene expression in normal tissue: TNRC6B

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in TNRC6B


DatabasePathway IDPathway Des.
reactomeR-HSA-1257604PIP3 activates AKT signaling
reactomeR-HSA-157118Signaling by NOTCH
reactomeR-HSA-162582Signal Transduction
reactomeR-HSA-1912408Pre-NOTCH Transcription and Translation
reactomeR-HSA-1912422Pre-NOTCH Expression and Processing
reactomeR-HSA-195721Signaling by WNT
reactomeR-HSA-211000Gene Silencing by RNA
reactomeR-HSA-212436Generic Transcription Pathway
reactomeR-HSA-2262752Cellular responses to stress
reactomeR-HSA-2559580Oxidative Stress Induced Senescence
reactomeR-HSA-2559583Cellular Senescence
reactomeR-HSA-2559585Oncogene Induced Senescence
reactomeR-HSA-3700989Transcriptional Regulation by TP53
reactomeR-HSA-3858494Beta-catenin independent WNT signaling
reactomeR-HSA-4086398Ca2+ pathway
reactomeR-HSA-426496Post-transcriptional silencing by small RNAs
reactomeR-HSA-5628897TP53 Regulates Metabolic Genes
reactomeR-HSA-5683057MAPK family signaling cascades
reactomeR-HSA-5687128MAPK6/MAPK4 signaling
reactomeR-HSA-6807070PTEN Regulation
reactomeR-HSA-73857RNA Polymerase II Transcription
reactomeR-HSA-74160Gene expression (Transcription)
reactomeR-HSA-8878171Transcriptional regulation by RUNX1
reactomeR-HSA-8934593Regulation of RUNX1 Expression and Activity
reactomeR-HSA-8936459RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
reactomeR-HSA-8939211ESR-mediated signaling
reactomeR-HSA-8943723Regulation of PTEN mRNA translation
reactomeR-HSA-8948700Competing endogenous RNAs (ceRNAs) regulate PTEN translation
reactomeR-HSA-8953897Cellular responses to external stimuli
reactomeR-HSA-9006925Intracellular signaling by second messengers
reactomeR-HSA-9006931Signaling by Nuclear Receptors
reactomeR-HSA-9018519Estrogen-dependent gene expression

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD6AM-5802
iGMDRD289Parthenolide1
iGMDRD77Itraconazole1
iGMDRD103SN-382
iGMDRD158NSC1415406
iGMDRD121GMX17781
iGMDRD137Indisulam2
iGMDRD251ML1621
iGMDRD300Tozasertib1
iGMDRD263AACOCF31
iGMDRD42Vorinostat1
iGMDRD322FK 8665
iGMDRD67PENFLURIDOL1
iGMDRD286Nsc 6328393
iGMDRD414MST-3124
iGMDRD329Merck606
iGMDRD424Tamatinib2
iGMDRD299ICL 6701
iGMDRD79Gemcitabine4
iGMDRD84Lovastatin acid2
iGMDRD330BRD41322
iGMDRD307Manumycin A2
iGMDRD177Teniposide2
iGMDRD123Isoevodiamine1
iGMDRD207Capsaicin1
iGMDRD885Compound 1102
iGMDRD870BRD636101
iGMDRD270Ciclosporin1
iGMDRD474Avrainvillamide3
iGMDRD8024-methylfasudil2
iGMDRD64Parbendazole2
iGMDRD268Cerulenin1
iGMDRD23Gossypol2
iGMDRD524ISX-92
iGMDRD100Zebularine2
iGMDRD74Idarubicin4
iGMDRD780PP-301
iGMDRD546BMS-7548074
iGMDRD781Sirolimus2
iGMDRD433Lexibulin2
iGMDRD151CHM-12
iGMDRD772BRD47702
iGMDRD394BX-7953
iGMDRD634SCHEMBL26080413
iGMDRD446LY 21832402
iGMDRD61Kinetin riboside2
iGMDRD152179324-69-71

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in TNRC6B

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