ULK2


Summary: This gene encodes a protein that is similar to a serine/threonine kinase in C. elegans which is involved in axonal elongation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a central proline/serine rich (PS) domain, and a C-terminal (C) domain. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Dec 2008].

Loading, please wait...
Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location

GO terms in ULK2


Loading, please wait...
Term Type
Evidence Type
GO Term ID
GO Des.
MF IBA GO:0004674 protein serine/threonine kinase activity
MF IDA GO:0004674 protein serine/threonine kinase activity
MF IPI GO:0005515 protein binding
MF IEA GO:0005524 ATP binding
CC IBA GO:0000407 phagophore assembly site
CC IBA GO:0005829 cytosol
Showing 1 to 6 of 19 rows rows per page

Gene expression in normal tissue: ULK2

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in ULK2


Loading, please wait...
Database
Pathway ID
Pathway Des.
kegg hsa04136 Autophagy - other - Homo sapiens (human)
kegg hsa04140 Autophagy - animal - Homo sapiens (human)
kegg hsa04150 mTOR signaling pathway - Homo sapiens (human)
pid mtor_4pathway mTOR signaling pathway
wikipathways WP1471 Target Of Rapamycin (TOR) Signaling
wikipathways WP2509 Nanoparticle triggered autophagic cell death
Showing 1 to 6 of 6 rows

Gene-Drug: Aster Plot


Loading, please wait...
Drug ID
Drug Name
Model Num.
iGMDRD772 BRD4770 3
iGMDRD425 ERASTIN 1
iGMDRD151 CHM-1 3
iGMDRD126 Tipifarnib 2
Showing 1 to 4 of 47 rows rows per page

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in ULK2

Loading, please wait...
Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

​​​​