GO terms in SIK2


Term TypeEvidence TypeGO Term IDGO Des.
BPIBAGO:0006468protein phosphorylation
BPIDAGO:0006468protein phosphorylation
BPIBAGO:0032007negative regulation of TOR signaling
BPIBAGO:0035556intracellular signal transduction
BPIDAGO:0035556intracellular signal transduction
BPIBAGO:0042149cellular response to glucose starvation
BPISSGO:0046626regulation of insulin receptor signaling pathway
BPIDAGO:0046777protein autophosphorylation
CCIBAGO:0005634nucleus
CCIBAGO:0005737cytoplasm
CCISSGO:0005737cytoplasm
CCIBAGO:0031588nucleotide-activated protein kinase complex
MFIDAGO:0000287magnesium ion binding
MFIBAGO:0004674protein serine/threonine kinase activity
MFIDAGO:0004674protein serine/threonine kinase activity
MFIPIGO:0005515protein binding
MFIDAGO:0005524ATP binding

Gene expression in normal tissue: SIK2

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in SIK2


DatabasePathway IDPathway Des.
kegghsa04922Glucagon signaling pathway - Homo sapiens (human)
pidlkb1_pathwayLKB1 signaling events

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD123Isoevodiamine3
iGMDRD211(1S,3R)-RSL35
iGMDRD945ML2143
iGMDRD424Tamatinib6
iGMDRD560MK-22062
iGMDRD148Pifithrin-mu5
iGMDRD584VER 1550082
iGMDRD246NPC263
iGMDRD300Tozasertib6
iGMDRD322FK 8664
iGMDRD82Quiflapon2
iGMDRD286Nsc 6328397
iGMDRD269Purmorphamine4
iGMDRD329Merck604
iGMDRD221Tamoxifen5
iGMDRD6AM-5803
iGMDRD289Parthenolide3
iGMDRD213SMR0000686505
iGMDRD481Dactolisib4
iGMDRD137Indisulam4
iGMDRD121GMX17782
iGMDRD634SCHEMBL26080414
iGMDRD201SKI II5
iGMDRD107Valdecoxib5
iGMDRD2PK-111951
iGMDRD193Fqi15
iGMDRD163all trans Retinoic Acid3
iGMDRD670ML 2105
iGMDRD546BMS-7548073
iGMDRD462OSI-906 (Linsitinib)1
iGMDRD433Lexibulin4
iGMDRD151CHM-11
iGMDRD126Tipifarnib5
iGMDRD866BRD18125
iGMDRD579PF7505
iGMDRD772BRD47705
iGMDRD599Salermide2
iGMDRD60Quinoclamine2
iGMDRD369TGX-1152
iGMDRD64Parbendazole6
iGMDRD690PRIMA-1MET7
iGMDRD268Cerulenin1
iGMDRD23Gossypol3
iGMDRD356PNU-746545
iGMDRD74Idarubicin3
iGMDRD730Kahalalide F2
iGMDRD399Selumetinib3
iGMDRD188Piperlongumine4
iGMDRD100Zebularine4
iGMDRD562Navitoclax2
iGMDRD506Fedratinib2
iGMDRD888Compound 447
iGMDRD885Compound 1102
iGMDRD441TW 372
iGMDRD474Avrainvillamide1
iGMDRD255SB2250021

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in SIK2

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