iGMDRD444


Canonical SMILES: C1CC2=CC=CC3=C2N(C1)C=C3C4C(C(=O)NC4=O)C5=CNC6=CC=CC=C65

InChI: InChI=1S/C23H19N3O2/c27-22-19(16-11-24-18-9-2-1-7-14(16)18)20(23(28)25-22)17-12-26-10-4-6-13-5-3-8-15(17)21(13)26/h1-3,5,7-9,11-12,19-20,24H,4,6,10H2,(H,25,27,28)/t19-,20-/m0/s1

InChI Key: UCEQXRCJXIVODC-PMACEKPBSA-N

Standard NameCHEMBLPubchem CIDDRUGBANK IDDrug StatusDrug Type
TivantinibCHEMBL2103882 11494400DB12200AloneSmall Molecule



Drug Pathways:

RTK signaling

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
132ADK3
4926NUMA12
23513SCRIB3
2956MSH61
5295PIK3R14
3551IKBKB3
57580PREX11
10013HDAC62
57472CNOT63
5966REL3
5159PDGFRB2
2042EPHA31
51804SIX42
57476GRAMD1B1
65217PCDH151
783CACNB22
50488MINK12
7010TEK1
839CASP63
2201FBN22
9794MAML12
3932LCK3
57194ATP10A3
8218CLTCL12
3791KDR1
836CASP33
2263FGFR21
4086SMAD11
5585PKN13
55437STRADB3
84181CHD63
7994KAT6A3
4089SMAD41
6134RPL103
10565ARFGEF12
64750SMURF22
6885MAP3K73
23604DAPK23
10186LHFPL61
1213CLTC2
4790NFKB12
867CBL1
6095RORA2
7301TYRO31
3229HOXC133
10010TANK2
22883CLSTN11
23389MED13L2
53904MYO3A1
10595ERN22
5581PRKCE2
100124696TEC2
53353LRP1B3
3557IL1RN3
2130EWSR12
6653SORL11
2065ERBB31
197259MLKL2
2073ERCC52
4763NF13
1612DAPK12
138474TAF1L3
23683PRKD33
1803DPP42

Gene in drug-gene network: Network Plot

Models in Tivantinib

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