iGMDRD269


Canonical SMILES: C1CCC(CC1)N2C=NC3=C2N=C(N=C3NC4=CC=C(C=C4)N5CCOCC5)OC6=CC=CC7=CC=CC=C76

InChI: InChI=1S/C31H32N6O2/c1-2-9-25(10-3-1)37-21-32-28-29(33-23-13-15-24(16-14-23)36-17-19-38-20-18-36)34-31(35-30(28)37)39-27-12-6-8-22-7-4-5-11-26(22)27/h4-8,11-16,21,25H,1-3,9-10,17-20H2,(H,33,34,35)

InChI Key: FYBHCRQFSFYWPY-UHFFFAOYSA-N

Standard NamePubchem CIDDrug StatusDrug Type
Purmorphamine5284330AloneSmall Molecule

Drug Targets:

SMO

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
132ADK2
5933RBL12
7161TP733
5546PRCC1
3708ITPR11
7272TTK2
8289ARID1A2
80070ADAMTS201
5934RBL22
1263PLK32
6597SMARCA42
7444VRK22
23235SIK24
10863ADAM282
1404HAPLN12
9232PTTG13
5467PPARD3
3456IFNB12
5465PPARA3
8784TNFRSF182
5664PSEN23
342667STAC23
5900RALGDS3
80129CCDC1701
51804SIX41
8643PTCH22
23191CYFIP11
29760BLNK3
158056MAMDC42
10087COL4A3BP1
659BMPR22
9472AKAP61
5165PDK33
139285AMER12
4058LTK3
5450POU2AF14
9794MAML13
83694RPS6KL11
3236HOXD102
11143KAT72
7704ZBTB162
2322FLT33
8218CLTCL12
65243ZFP69B2
984CDK11B1
6280S100A93
2668GDNF3
4139MARK12
5606MAP2K31
7043TGFB31
100130933SMIM63
29951PDZRN41
2189FANCG3
5156PDGFRA2
673BRAF2
4790NFKB11
83452RAB33B1
2078ERG1
867CBL2
9451EIF2AK32
9509ADAMTS23
23476BRD42
5728PTEN1
667DST2
284086NEK82
6146RPL222
79834PEAK12
7465WEE13
558AXL1
5581PRKCE3
2690GHR1
8031NCOA41
53353LRP1B1
7293TNFRSF45
54101RIPK42
4067LYN2
80216ALPK11
2122MECOM2
4217MAP3K52
5586PKN21
10494STK252
11086ADAM293
581BAX1
4763NF11
5260PHKG11
23683PRKD33
3679ITGA72
1436CSF1R1
2886GRB73

Gene in drug-gene network: Network Plot

Models in Purmorphamine

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