iGMDRD82


Canonical SMILES: CC(C)(C)SC1=C(N(C2=C1C=C(C=C2)OCC3=NC4=CC=CC=C4C=C3)CC5=CC=C(C=C5)Cl)CC(C)(C)C(=O)O

InChI: InChI=1S/C34H35ClN2O3S/c1-33(2,3)41-31-27-18-26(40-21-25-15-12-23-8-6-7-9-28(23)36-25)16-17-29(27)37(20-22-10-13-24(35)14-11-22)30(31)19-34(4,5)32(38)39/h6-18H,19-21H2,1-5H3,(H,38,39)

InChI Key: NZOONKHCNQFYCI-UHFFFAOYSA-N

Standard NameCHEMBLPubchem CIDDrug StatusDrug Type
QuiflaponCHEMBL16596 CHEMBL313489 60923AloneSmall Molecule

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
331XIAP6
6664SOX113
8019BRD33
5027P2RX73
79054TRPM82
7128TNFAIP33
6491STIL3
21ABCA31
6581SLC22A31
132ADK2
6774STAT33
8929PHOX2B3
2339FNTA3
1520CTSS4
57554LRRC73
7272TTK3
2100ESR23
80070ADAMTS202
3939LDHA3
5934RBL22
25778DSTYK4
4928NUP982
79092CARD145
7764ZNF2173
3069HDLBP3
56776FMN21
4313MMP22
23235SIK22
3320HSP90AA15
7253TSHR3
27ABL23
2241FER3
4149MAX3
7048TGFBR22
112858TP53RK2
1813DRD26
1387CREBBP10
5756TWF11
5788PTPRC3
5579PRKCB3
31ACACA1
9048ARTN2
4851NOTCH12
5314PKHD11
10746MAP3K23
23522KAT6B5
55728N4BP22
440279UNC13C3
4610MYCL9
342977NANOS31
152137CCDC503
8767RIPK23
2051EPHB62
3714JAG22
32ACACB2
329BIRC26
2242FES2
6041RNASEL2
8313AXIN23
6733SRPK23
2042EPHA32
1050CEBPA3
199699DAND53
5330PLCB21
10188TNK21
9636ISG153
83990BRIP11
238ALK2
22858ICK2
287015TRIM422
6663SOX103
54899PXK4
23387SIK32
1456CSNK1G33
6416MAP2K43
1452CSNK1A15
6709SPTAN13
8215DVL1P13
6098ROS13
130497OSR16
3685ITGAV2
139285AMER18
8148TAF155
53942CNTN52
9564BCAR12
8038ADAM121
1496CTNNA24
5450POU2AF15
23152CIC3
2272FHIT2
10290SPEG2
10018BCL2L115
648BMI14
2099ESR11
572BAD3
130399ACVR1C3
225689MAPK152
9639ARHGEF101
65243ZFP69B2
105ADARB22
863CBFA2T33
8874ARHGEF71
1102RCBTB21
55437STRADB2
2309FOXO32
7038TG3
369ARAF2
3187HNRNPH11
136332LRGUK2
50945TBX224
676BRDT3
5650KLK72
5871MAP4K21
2081ERN13
4026LPP3
23269MGA2
23469PHF33
285220EPHA62
546ATRX3
5069PAPPA1
10535RNASEH2A2
57144PAK53
9972NUP1532
50615IL21R2
1000CDH25
57154SMURF12
3458IFNG4
1956EGFR6
4318MMP93
3065HDAC11
11064CNTRL1
2624GATA22
90427BMF2
8795TNFRSF10B3
894CCND22
5462POU5F1B1
1594CYP27B13
8900CCNA12
1544CYP1A23
27330RPS6KA63
203102ADAM322
84879MFSD2A10
3315HSPB11
780DDR11
57538ALPK33
8924HERC22
65268WNK23
6095RORA3
5294PIK3CG3
7849PAX81
5979RET6
10253SPRY23
654780LOC6547806
8491MAP4K33
9509ADAMTS24
1869E2F13
667DST2
3554IL1R14
85409NKD23
8301PICALM3
1445CSK3
5582PRKCG2
995CDC25C4
7454WAS2
7036TFR23
55356SLC22A153
85415RHPN23
29959NRBP12
53904MYO3A2
9372ZFYVE93
10249GLYAT2
8394PIP5K1A3
23305ACSL61
1643DDB22
54738FEV3
4297KMT2A1
5291PIK3CB4
9021SOCS32
10111RAD503
53353LRP1B1
55289ACOXL1
5335PLCG12
3624INHBA3
3579CXCR21
55007FAM118A6
5170PDPK11
57007ACKR36
23139MAST21
79837PIP4K2C2
3709ITPR21
8550MAPKAPK51
1030CDKN2B1
5932RBBP82
2122MECOM2
5087PBX13
4217MAP3K53
7403KDM6A6
3716JAK12
4299AFF11
3092HIP13
4763NF14
5260PHKG15
6886TAL13
4629MYH111
30811HUNK3
10048RANBP92
1608DGKG2
6868ADAM171
2178FANCE2
83732RIOK12
3895KTN11
56155TEX142
5624PROC1

Gene in drug-gene network: Network Plot

Models in Quiflapon

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