iGMDRD309


Canonical SMILES: CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCC=C)C)OC)OC(=O)N)C)C)O)OC

InChI: InChI=1S/C31H43N3O8/c1-8-12-33-26-21-13-17(2)14-25(41-7)27(36)19(4)15-20(5)29(42-31(32)39)24(40-6)11-9-10-18(3)30(38)34-22(28(21)37)16-23(26)35/h8-11,15-17,19,24-25,27,29,33,36H,1,12-14H2,2-7H3,(H2,32,39)(H,34,38)/b11-9+,18-10+,20-15+/t17-,19+,24+,25+,27-,29+/m1/s1

InChI Key: AYUNIORJHRXIBJ-HTLBVUBBSA-N

Standard NameCHEMBLPubchem CIDDrug StatusDrug Type
17AAGCHEMBL126955 6440180AloneSmall Molecule

Drug Targets:

HSP90

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
100113407TMEM170B2
8618CADPS1
4990SIX61
254956MORN51
102724386LINC013931
283514SIAH31
55964SEPT31
6545SLC7A41
222183SRRM31
10533ATG71
11199ANXA102
9846GAB22
224ALDH3A21
162540SPPL2C2
57722IGDCC41
106479415RN7SL526P1
91653BOC1
2956MSH61
493861EID31
138199CARNMT12
414134NANOGP61
7991TUSC31
400955LINC011222
79788ZNF6651
100507043TUNAR1
83539CHST91
9149DYRK1B1
3845KRAS1
122060SLAIN11
347733TUBB2B1
5295PIK3R11
2100ESR21
57453DSCAML12
9666DZIP31
64101LRRC41
441631TSPAN112
8266UBL4A2
8577TMEFF11
10519CIB12
158038LINGO21
25759SHC21
51129ANGPTL41
106480267COX6CP132
57709SLC7A141
9806SPOCK21
114818KLHL291
6597SMARCA42
79176FBXL151
256051ZNF5492
58525WIZ1
107075279MTND3P171
29948OSGIN12
9429ABCG21
340527NHSL21
29062WDR911
3416IDE1
441355MIR2052HG1
25828TXN23
8309ACOX21
23732FRRS1L1
5079PAX52
4771NF21
653483AFDN-DT1
6598SMARCB11
6051RNPEP1
9922IQSEC11
23213SULF11
164045HFM11
152330CNTN41
2195FAT11
7253TSHR1
3195TLX11
727676SNORD1182
222223KIAA1324L2
55969RAB5IF1
706TSPO2
27023FOXB11
27069GHITM2
29114TAGLN31
249ALPL1
402569KPNA71
202374STK32A1
10539GLRX31
148206ZNF7141
1813DRD21
100129842ZNF7371
100422918MIR31672
40ASIC21
5782PTPN121
90293KLHL131
10013HDAC61
9123SLC16A31
10178TENM11
134430WDR361
388327C17orf1002
143686SESN31
55699IARS21
55863TMEM126B1
115677NOSTRIN1
7617ZNF662
105378716LINC015621
8242KDM5C1
5136PDE1A1
122592KRT18P61
54504CPVL2
89792GAL3ST31
400120SERTM11
65055REEP11
254439C11orf861
1837DTNA1
1646AKR1C22
4851NOTCH11
55294FBXW71
6880TAF91
284443ZNF4931
1021CDK61
22839DLGAP41
2257FGF121
3242HPD1
100129972NPM1P471
7852CXCR42
29106SCG32
6282S100A112
284307ZIK11
4610MYCL1
80728ARHGAP391
816CAMK2B1
9912ARHGAP441
266703ASH2LP12
57556SEMA6A1
100861556YBX1P32
5552SRGN2
2596GAP431
440515ZNF5061
1645AKR1C12
51268PIPOX1
55790CSGALNACT11
646643SBK21
6334SCN8A1
147166TRIM16L1
84749USP301
55220KLHDC8A1
55753OGDHL2
64841GNPNAT12
84527ZNF5591
534ATP6V1G21
4300MLLT31
2830GPR62
106479317RN7SL262P2
54606DDX562
100505683LINC014311
9762LZTS31
51343FZR11
4948OCA21
10777ARPP211
4135MAP61
199692ZNF6271
26033ATRNL12
84775ZNF6071
9314KLF41
3745KCNB12
108ADCY21
60468BACH22
59084ENPP52
54796BNC21
238ALK2
7428VHL1
57528KCTD161
57633LRRN12
2064ERBB22
103910MYL12B2
22881ANKRD62
282553AUTS82
23114NFASC1
83707TRPT11
91156IGFN11
3763KCNJ61
340543TCEAL51
6636SNRPF1
2052EPHX12
23191CYFIP11
23096IQSEC21
440730TRIM671
8822FGF171
51617NSG21
11255HRH32
283576ZDHHC221
84440RAB11FIP41
129881CCDC1731
6416MAP2K41
22949PTGR12
23348DOCK91
8714ABCC32
106478957DDX39B-AS12
273AMPH1
1641DCX1
79540OR7E89P2
255928SYT142
140809SRXN12
6464SHC12
9717SEC14L51
10836NPM1P111
54437SEMA5B2
1949EFNB31
2778GNAS1
27253PCDH171
57512GPR1581
10580SORBS11
54511HMGCLL11
139285AMER11
9498SLC4A81
100132994CXorf49B1
399697CTXN22
6320CLEC11A1
347252IGFBPL11
9027NAT82
51209RAB9B2
27145FILIP11
5450POU2AF11
9829DNAJC61
27344PCSK1N2
7681MKRN31
27239GPR1621
84707BEX22
5522PPP2R2C1
5243ABCB12
1029CDKN2A2
10590SCGN1
6272SORT12
152404IGSF111
10683DLL31
56242ZNF2531
389792IER5L2
6297SALL22
23584VSIG21
441024MTHFD2L1
100130700TP53TG3HP1
284439SLC25A421
284764FTLP32
285203EOGT2
861RUNX11
6999TDO21
25862USP491
55505NOP101
66000TMEM1081
100271204RPL5P252
27445PCLO2
3932LCK1
23705CADM11
57101ANO21
7157TP531
25830SULT4A12
645BLVRB1
6794STK113
84803GPAT32
8541PPFIA31
7562ZNF7082
2259FGF141
11075STMN22
140831ZSWIM32
4292MLH11
54498SMOX1
2151F2RL22
140706CCM2L1
54753ZNF8531
1400CRMP11
1019CDK41
9278ZBTB221
101929402EXTL3-AS11
340888AKR1B10P11
641516KC61
102723513ZNF30-AS11
387978LINC015511
8874ARHGEF71
126069ZNF4911
55034MOCOS2
10516FBLN51
58512DLGAP32
84623KIRREL31
100128252ZNF667-AS11
23284ADGRL31
9312KCNB21
348156PKD1P51
55530SVOP1
1728NQO12
7423VEGFB1
26984SEC22A1
170554DYNLT3P12
9108MTMR71
4440MSI12
54043MYL6P12
28989NTMT11
124925SEZ62
80034CSRNP31
55556ENOSF11
57578UNC791
9832JAKMIP21
8744TNFSF92
344887NMRAL2P2
8801SUCLG22
284459HKR11
4908NTF31
4089SMAD42
57711ZNF5292
6970TRGJP2
400961PAIP2B1
51164DCTN41
100847000MIR55791
5100PCDH81
58524DMRT31
7439BEST11
7594ZNF432
100421657HNRNPDLP41
103695363FOXG1-AS11
26154ABCA121
5269SERPINB61
3417IDH11
2047EPHB11
6855SYP1
100129976BRI3BPP12
374899ZNF8291
83723FAM57B1
4097MAFG1
92979MARCH92
8731RNMT1
4072EPCAM1
9750RIPOR22
147923ZNF4201
5290PIK3CA4
10283CWC271
653238GTF2H2B1
57834CYP4F111
10687PNMA21
157922CAMSAP11
204777IGLJCOR181
675BRCA21
106479585RNU4-60P2
348303SELENOV1
9378NRXN11
1956EGFR1
100419978HMGB1P462
6853SYN11
22875ENPP42
153657TTC23L1
841CASP81
4609MYC1
101927720ZNF793-AS12
90113VWA5B21
100874025GFOD1-AS12
5789PTPRD1
2890GRIA11
148198ZNF981
84448ABLIM21
100130933SMIM61
8795TNFRSF10B1
3746KCNC12
340596LHFPL12
10472ZBTB182
1031CDKN2C1
7757ZNF2081
91120ZNF6822
147646C19orf841
5156PDGFRA1
106481966BNIP3P281
218ALDH3A12
23108RAP1GAP21
100873974LINC025861
7917BAG62
27345KCNMB41
51440HPCAL41
8237USP111
10000AKT31
6710SPTB1
648947AKR1C7P2
58528RRAGD2
56271BEX42
79605PGBD51
673BRAF2
4790NFKB11
947CD342
1788DNMT3A1
57150SMIM81
81849ST6GALNAC51
3315HSPB11
100874235CACNA1C-AS21
79258MMEL11
23148NACAD1
100873566RNA5SP5151
84467FBN31
57216VANGL21
200150PLD51
28987NOB12
26084ARHGEF261
100874014NAV2-AS21
286527TMSB15B1
29109FHOD11
119369NUDT9P12
78997GDAP1L12
27292DIMT12
342357ZKSCAN21
7076TIMP12
162963ZNF6101
10231RCAN22
157739TDH1
361AQP41
8942KYNU1
51555PEX5L1
388011LINC015501
386758ZNF582-AS11
771CA121
146206CARMIL22
60370AVPI12
147645VSIG10L1
8644AKR1C31
10312TCIRG11
642968FAM163B2
57540DISP31
196475RMST1
55521TRIM361
90249UNC5A1
1995ELAVL31
30818KCNIP31
2900GRIK41
5728PTEN2
208AKT21
648809EFL1P11
54550NECAB21
9705ST181
8120AP3B21
79570NKAIN11
3554IL1R11
219539YPEL41
10415SNAI1P11
80164PRR362
100128541ATP6V1G1P21
392547CROCCP12
728116ZBTB8B1
56647BCCIP1
8453CUL21
124961ZFP32
148898ZNF436-AS11
57484RNF1502
7712ZNF1571
252884ZNF3962
55738ARFGAP11
221395ADGRF51
154215NKAIN21
4935GPR1431
90134KCNH71
64222TOR3A1
100462990HSPD1P212
9582APOBEC3B2
11095ADAMTS81
56961SHD1
349136WDR861
64399HHIP1
171023ASXL11
8927BSN1
343702XKR72
28778IGLV6-572
6326SCN2A1
83596BCL2L121
442319ZNF7272
4753NELL22
221527ZBTB121
440051KRTAP5-112
55693KDM4D1
84059ADGRV11
57655GRAMD1A1
167838TXLNB1
9139CBFA2T21
402116PKP4P12
6397SEC14L11
8655DYNLL11
1141CHRNB21
10900RUNDC3A2
53826FXYD61
22843PPM1E1
120114FAT32
677799SNORA111
51560RAB6B2
56853CELF41
3780KCNN11
23305ACSL62
54738FEV2
1113CHGA1
9911TMCC22
107984161ARL4AP31
51151SLC45A22
1380CR21
79906MORN11
84465MEGF111
4741NEFM1
54768HYDIN1
170961ANKRD241
2775GNAO11
23359FAM189A11
26051PPP1R16B1
147741ZNF5601
50801KCNK41
352954CASTOR32
23201FAM168A1
100616484MIR44701
51078THAP41
343450KCNT21
10893MMP242
778CACNA1F1
5158PDE6B2
63976PRDM161
283165KIRREL3-AS32
100529215ZNF559-ZNF1771
283455KSR21
7086TKT1
222662LHFPL51
159989DEUP11
100132815IPO5P11
2730GCLM2
6328SCN3A1
7122CLDN51
390927ZNF7932
9148NEURL11
63967CLSPN1
1244ABCC22
57016AKR1B101
341883LRRC91
221935SDK12
139599MAGEE22
90594ZNF4392
23380SRGAP21
55512SMPD31
9145SYNGR11
100616437MIR13431
84684INSM22
3717JAK21
9283GPR37L11
138428PTRH11
340595RTL42
605BCL7A2
51704GPRC5B1
83482SCRT12
100533181FXYD6-FXYD21
7358UGDH2
145407ARMH41
56851EMC71
4033LRMP1
9369NRXN31
84866TMEM251
153020RASGEF1B1
64852TUT11
9737GPRASP11
8877SPHK12
79608RIC32
147463ANKRD291
196528ARID21
5452POU2F21
5925RB11
643401PURPL1
4893NRAS2
8629JRK1
135924OR9A22
388125C2CD4B1
9892SNAP912
862RUNX1T11
55786ZNF4151
6900CNTN21
6579SLCO1A21
11281POU6F21
7403KDM6A1
100506930LINC006651
1857DVL31
2534FYN1
107075252RPL12P492
23036ZNF2921
10935PRDX32
29942PURG2
144453BEST31
197259MLKL2
7040TGFB11
9066SYT71
10568SLC34A21
3309HSPA51
8517IKBKG1
100126347MIR8871
259285TAS2R392
9610RIN11
29993PACSIN12
254263CNIH21
2562GABRB31
10021HCN42
100506237NKX2-1-AS11
81558FAM117A2
9863MAGI21
346606MOGAT31
135295SRSF122
2261FGFR31
25837RAB261
23072HECW11
100873562RNA5SP5111
79931TNIP32
79632FAM184A2
57631LRCH21
321APBA21
79290OR13A11
2348FOLR11
26077DKFZP434H1682
154661RUNDC3B1
595CCND11
100271584RPS27P252
10613ERLIN11
4763NF11
1612DAPK11
8128ST8SIA21
79083MLPH1
4613MYCN1
2512FTL2
54537SHLD21
100420574VDAC2P42
1840DTX11
65975STK332
10418SPON11
23657SLC7A112
30811HUNK1
388419BTBD171
11135CDC42EP12
163223ZNF6761
100312830VN1R85P1
29118DDX251
3265HRAS1
5457POU4F12
4193MDM21
101929127PGM5P3-AS11
6586SLIT31
2899GRIK31
128408BHLHE232
11196SEC23IP1
101929623LINC012151
2820GPD21
29110TBK12
29767TMOD22
101928991CCDC92B2
1499CTNNB11
3162HMOX12
441061MARCH111
5602MAPK101
2146EZH21
1271CNTFR1
148203ZNF7382
643155SMIM151
5624PROC1
284424MIR7-3HG1
8715NOL41
79369B3GNT41

Gene in drug-gene network: Network Plot

Models in 17AAG

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