iGMDRD187


Canonical SMILES: CC(C)(C)C1=CC2=C(C=C1)C=C(C(=C2)C#N)C#N

InChI: InChI=1S/C16H14N2/c1-16(2,3)15-5-4-11-6-13(9-17)14(10-18)7-12(11)8-15/h4-8H,1-3H3

InChI Key: MKILROQBJOOZKC-UHFFFAOYSA-N

Standard NamePubchem CIDDrug StatusDrug Type
BRD9876613000AloneSmall Molecule

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
331XIAP3
27102EIF2AK11
8999CDKL24
8019BRD32
5027P2RX72
79848CSPP12
6491STIL1
10987COPS53
9261MAPKAPK22
4926NUMA12
840CASP73
114801TMEM200A1
5546PRCC3
4168MCF22
2956MSH61
57679ALS21
150465TTL2
3708ITPR13
9706ULK23
7272TTK3
4750NEK15
5295PIK3R14
23097CDK191
8289ARID1A3
6351CCL42
26511CHIC21
51129ANGPTL43
84700MYO18B3
3431SP1103
2475MTOR3
9475ROCK24
6597SMARCA41
3326HSP90AB13
4036LRP21
10395DLC14
5133PDCD14
9530BAG42
7444VRK24
390502SERPINA25
56776FMN22
5079PAX53
4313MMP23
10863ADAM283
6598SMARCB13
1607DGKB1
1272CNTN13
3320HSP90AA11
3066HDAC21
57172CAMK1G1
22821RASA33
6887TAL22
54822TRPM71
114783LMTK31
202374STK32A2
1387CREBBP5
11329STK383
5788PTPRC2
10013HDAC61
7133TNFRSF1B1
9699RIMS22
51755CDK123
1111CHEK14
2977GUCY1A24
23617TSSK23
5899RALB1
7173TPO1
55294FBXW72
641BLM1
4361MRE113
284521OR2L136
84033OBSCN2
5900RALGDS3
256646NUTM11
9693RAPGEF23
23012STK38L3
32ACACB1
3556IL1RAP3
22806IKZF33
10342TFG1
4005LMO23
22984PDCD113
5468PPARG2
80351TNKS23
23255MTCL12
730249ACOD13
2908NR3C12
83990BRIP15
51804SIX43
3688ITGB16
9098USP62
7424VEGFC3
2045EPHA71
140901STK352
1992SERPINB12
375449MAST42
4752NEK33
22858ICK2
983CDK13
57476GRAMD1B2
83983TSSK63
7486WRN3
23191CYFIP12
440730TRIM673
5573PRKAR1A2
783CACNB24
4140MARK31
92ACVR2A1
57510XPO52
5286PIK3C2A1
25989ULK33
6709SPTAN12
6793STK103
5591PRKDC2
8859STK191
659BMPR24
6098ROS11
9472AKAP63
54437SEMA5B2
2778GNAS2
51433ANAPC51
80243PREX23
8945BTRC4
139285AMER11
83903HASPIN2
4087SMAD23
7533YWHAH5
5289PIK3C31
5450POU2AF12
2272FHIT2
2066ERBB43
904CCNT11
5327PLAT1
5863RGL22
79442LRRC23
10413YAP11
2201FBN22
7184HSP90B11
5108PCM11
23048FNBP11
27436EML42
157753TMEM744
57523NYNRIN5
5336PLCG21
58508KMT2C2
7157TP531
7704ZBTB161
79058ASPSCR12
4855NOTCH44
4857NOVA13
25836NIPBL3
397ARHGDIB6
356FASLG3
3000GUCY2D1
4086SMAD11
4869NPM12
64386MMP253
863CBFA2T34
7038TG3
369ARAF2
4921DDR22
2177FANCD23
5077PAX32
55589BMP2K3
65125WNK15
4436MSH22
6035RNASE13
7175TPR3
80205CHD94
2000ELF46
4437MSH33
4089SMAD42
7204TRIO2
9252RPS6KA51
78989COLEC111
23373CRTC13
5727PTCH11
51366UBR53
3426CFI2
23678SGK32
5606MAP2K31
5297PI4KA3
501ALDH7A13
64840PORCN2
1198CLK32
3239HOXD133
2187FANCB1
3562IL32
6046BRD21
3720JARID24
2931GSK3A2
8202NCOA33
4293MAP3K93
26524LATS25
253260RICTOR1
64919BCL11B2
675BRCA23
7075TIE15
3065HDAC13
4609MYC3
90956ADCK23
2624GATA23
3308HSPA43
5789PTPRD2
8021NUP2144
26278SACS3
51265CDKL33
6446SGK16
5747PTK22
5156PDGFRA2
7443VRK11
27330RPS6KA65
3949LDLR1
203102ADAM321
673BRAF1
57082KNL12
1981EIF4G14
1213CLTC3
6011GRK14
1769DNAH82
22976PAXIP12
23532PRAME2
780DDR12
8924HERC23
120892LRRK24
89795NAV31
6095RORA7
93273LEMD13
8029CUBN3
5128CDK171
5294PIK3CG1
5979RET3
9321TRIP113
664BNIP32
8491MAP4K31
55290BRF23
8621CDK132
23598PATZ12
23049SMG13
10010TANK2
8312AXIN14
10752CHL13
23476BRD43
7030TFE32
1316KLF63
8888MCM3AP2
55120FANCL1
100187828HBD1
115701ALPK21
660BMX3
352909DNAAF33
1950EGF2
2264FGFR41
177AGER6
5896RAG13
23090ZNF4233
3899AFF34
6498SKIL1
1018CDK36
7465WEE13
6789STK41
23332CLASP13
10257ABCC43
54904NSD31
8648NCOA13
79012CAMKV2
10249GLYAT2
5532PPP3CB1
22843PPM1E3
286151FBXO432
57820CCNB1IP16
5291PIK3CB2
4619MYH11
332BIRC51
57680CHD82
1399CRKL1
64764CREB3L23
10111RAD503
55289ACOXL3
3181HNRNPA2B12
1281COL3A12
283455KSR22
6093ROCK13
3557IL1RN2
2776GNAQ1
7291TWIST11
4628MYH102
5927KDM5A3
5587PRKD14
1719DHFR3
57007ACKR33
3717JAK22
22982DIP2C3
7227TRPS13
6778STAT63
4067LYN5
65267WNK33
4772NFATC11
3552IL1A2
80216ALPK13
5932RBBP81
3977LIFR6
4261CIITA1
170685NUDT106
2122MECOM6
3662IRF41
3815KIT2
5925RB12
4217MAP3K52
1209CLPTM11
63923TNN3
2074ERCC62
5324PLAG11
862RUNX1T15
7403KDM6A4
7508XPC1
2258FGF133
5586PKN21
3488IGFBP51
3480IGF1R6
4299AFF13
2651GCNT22
2073ERCC54
4040LRP63
55422ZNF3312
581BAX1
79966SCD52
55746NUP1336
595CCND13
4763NF12
8814CDKL11
55791LRIF12
1840DTX11
65975STK332
10891PPARGC1A2
440270GOLGA8B1
57096RPGRIP11
94ACVRL14
2044EPHA53
5287PIK3C2B2
4629MYH113
699BUB11
7294TXK2
83732RIOK11
3895KTN11
1499CTNNB13
3440IFNA21
167359NIM1K3
5685PSMA43

Gene in drug-gene network: Network Plot

Models in BRD9876

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