iGMDRD772


Canonical SMILES: COC(=O)C1=CC2=C(C=C1)N(C(=N2)NC(=O)C3=CC=CC=C3)CCCC4=CC=CC=C4

InChI: InChI=1S/C25H23N3O3/c1-31-24(30)20-14-15-22-21(17-20)26-25(27-23(29)19-12-6-3-7-13-19)28(22)16-8-11-18-9-4-2-5-10-18/h2-7,9-10,12-15,17H,8,11,16H2,1H3,(H,26,27,29)

InChI Key: UCGWYCMPZXDHNR-UHFFFAOYSA-N

Standard NamePubchem CIDDrug StatusDrug Type
BRD477072193900AloneSmall Molecule

Drug Targets:

EHMT2

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
331XIAP6
1105CHD12
6664SOX116
8019BRD31
10903MTMR113
79848CSPP12
10221TRIB13
8444DYRK32
6581SLC22A33
132ADK9
3383ICAM11
6774STAT32
5546PRCC2
2339FNTA3
1520CTSS3
57554LRRC76
9706ULK23
7272TTK6
93ACVR2B3
3845KRAS3
8289ARID1A2
8573CASK2
3939LDHA2
5934RBL22
2335FN13
4928NUP984
79092CARD145
4352MPL5
6938TCF123
6597SMARCA41
150209AIFM31
3551IKBKB2
4036LRP23
5241PGR2
5133PDCD11
3069HDLBP3
390502SERPINA23
5754PTK72
23235SIK25
3320HSP90AA15
5218CDK143
55781RIOK23
7253TSHR3
5298PI4KB3
2241FER2
9816URB26
4092SMAD73
577ADGRB32
1387CREBBP11
5756TWF12
2043EPHA43
5788PTPRC6
5579PRKCB6
11200CHEK26
31ACACA1
10178TENM12
85021REPS13
29998BICRA2
8295TRRAP3
10438C1D2
9024BRSK22
5159PDGFRB3
2033EP3003
6927HNF1A3
641BLM2
10746MAP3K23
23522KAT6B7
54477PLEKHA52
440279UNC13C3
4610MYCL5
4301AFDN1
816CAMK2B2
55819RNF1303
7025NR2F12
2051EPHB62
8549LGR52
6256RXRA2
3714JAG22
329BIRC26
26353HSPB85
166614DCLK22
4005LMO21
6041RNASEL3
200576PIKFYVE2
8313AXIN26
1050CEBPA3
116986AGAP23
199699DAND53
114548NLRP33
10188TNK22
29904EEF2K3
83990BRIP13
7088TLE12
284217LAMA13
83931STK403
171019ADAMTS192
2064ERBB21
85443DCLK33
287015TRIM428
65217PCDH151
9020MAP3K143
23387SIK32
783CACNB22
5127CDK163
1452CSNK1A12
29760BLNK3
57510XPO52
6709SPTAN13
8215DVL1P15
1973EIF4A13
2068ERCC23
6464SHC13
659BMPR22
6098ROS18
9472AKAP61
2778GNAS2
3685ITGAV2
472ATM1
3418IDH23
575ADGRB12
53942CNTN54
4087SMAD22
84433CARD112
9564BCAR12
4058LTK2
54986ULK41
1123CHN14
1496CTNNA23
5450POU2AF18
91461PKDCC3
898CCNE11
2050EPHB43
2272FHIT4
2066ERBB42
5863RGL22
9319TRIP133
139728PNCK3
9794MAML13
27436EML42
8576STK163
11143KAT72
28514DLL13
58508KMT2C3
648BMI13
2099ESR12
7704ZBTB162
6794STK114
8218CLTCL12
836CASP32
130399ACVR1C6
5585PKN15
7249TSC23
65243ZFP69B5
9967THRAP32
105ADARB23
5604MAP2K13
64386MMP253
863CBFA2T33
1555CYP2B61
1102RCBTB21
55437STRADB3
2309FOXO32
2177FANCD23
65125WNK15
57591MRTFA3
50945TBX227
652BMP42
676BRDT3
1656DDX62
5871MAP4K23
80205CHD92
8115TCL1A3
2081ERN16
57578UNC792
8997KALRN3
23269MGA2
3643INSR3
57551TAOK12
23469PHF32
8288EPX3
2668GDNF3
2737GLI32
7204TRIO2
78989COLEC112
5727PTCH12
9448MAP4K42
285220EPHA64
546ATRX2
6134RPL103
5069PAPPA3
10926DBF44
10535RNASEH2A3
64840PORCN3
57144PAK51
440275EIF2AK42
9972NUP1533
4293MAP3K92
90ACVR12
5366PMAIP13
7043TGFB33
57154SMURF12
3458IFNG3
28958COA33
7075TIE12
1956EGFR2
157680VPS13B2
4318MMP91
841CASP85
4609MYC3
64333ARHGAP91
11064CNTRL2
2624GATA22
5599MAPK83
8021NUP2143
8013NR4A33
90427BMF2
4684NCAM12
283629TSSK43
5462POU5F1B2
51265CDKL32
5663PSEN11
79759ZNF6682
3635INPP5D2
1653DDX12
8900CCNA11
7917BAG62
1544CYP1A26
27330RPS6KA62
23005MAPKBP13
1981EIF4G11
1213CLTC3
84879MFSD2A5
1769DNAH83
22976PAXIP12
23532PRAME2
4863NPAT3
780DDR15
83452RAB33B2
57538ALPK33
8924HERC22
6469SHH3
339345NANOS24
120892LRRK22
65268WNK26
7027TFDP13
6095RORA2
146057TTBK23
93273LEMD13
8178ELL3
5294PIK3CG3
1024CDK82
5979RET6
10253SPRY23
9451EIF2AK32
8491MAP4K33
55290BRF23
9509ADAMTS23
266747RGL42
8621CDK132
5563PRKAA22
10010TANK6
8312AXIN12
10752CHL13
7030TFE32
2316FLNA3
7155TOP2B3
80124VCPIP12
667DST2
3554IL1R15
83666PARP93
5305PIP4K2A2
23542MAPK8IP25
352909DNAAF35
4317MMP83
1950EGF2
5896RAG13
2870GRK64
23090ZNF4232
79834PEAK12
6789STK43
7036TFR26
55356SLC22A153
55359STYK13
2277VEGFD2
23411SIRT13
9372ZFYVE96
10249GLYAT2
128869PIGU2
1643DDB22
54738FEV3
2072ERCC42
5588PRKCQ2
51151SLC45A26
5291PIK3CB4
7248TSC12
332BIRC52
57680CHD82
2041EPHA12
2317FLNB2
5395PMS23
1789DNMT3B2
140913PPIAP103
53353LRP1B2
1281COL3A12
2049EPHB33
283455KSR24
5335PLCG12
131890GRK73
55007FAM118A5
10734STAG33
5589PRKCSH2
57448BIRC62
57007ACKR36
8317CDC72
3717JAK22
22982DIP2C2
2157F82
79837PIP4K2C2
57147SCYL32
6778STAT63
8899PRPF4B2
8550MAPKAPK53
3984LIMK12
80216ALPK13
4261CIITA3
4330MN13
444ASPH3
11076TPPP1
7913DEK2
8536CAMK13
2122MECOM4
51167CYB5R46
1760DMPK2
9894TELO23
63923TNN3
3691ITGB42
7403KDM6A2
2308FOXO13
2258FGF133
8841HDAC32
4638MYLK2
3716JAK12
3480IGF1R3
2011MARK22
23092ARHGAP262
10494STK253
139604MAGEB162
84197POMK2
8711TNK13
4040LRP62
4841NONO3
9625AATK1
10891PPARGC1A3
57096RPGRIP13
4629MYH113
23112TNRC6B2
27255CNTN62
2444FRK1
56155TEX144
11035RIPK33
5685PSMA43

Gene in drug-gene network: Network Plot

Models in BRD4770

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