iGMDRD414


Canonical SMILES: C1=CC(=CC(=C1)NC(=O)C2=C(C(=CC=C2)O)O)NC(=O)C3=C(C(=CC=C3)O)O

InChI: InChI=1S/C20H16N2O6/c23-15-8-2-6-13(17(15)25)19(27)21-11-4-1-5-12(10-11)22-20(28)14-7-3-9-16(24)18(14)26/h1-10,23-26H,(H,21,27)(H,22,28)

InChI Key: MIQUEZGHEJGPJB-UHFFFAOYSA-N

Standard NameCHEMBLPubchem CIDDrug StatusDrug Type
MST-312CHEMBL2170856 10385100AloneSmall Molecule

Drug Targets:

TERT

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
64901RANBP172
7514XPO11
79848CSPP12
7837PXDN2
79054TRPM82
7128TNFAIP32
10987COPS57
26191PTPN222
7750ZMYM27
4926NUMA12
11183MAP4K52
29101SSU723
2986GUCY2F2
79947DHDDS2
57679ALS22
1588CYP19A12
9149DYRK1B3
347365ITIH63
1138CHRNA53
23552CDK203
8289ARID1A2
80070ADAMTS202
5593PRKG23
4312MMP13
6597SMARCA46
150209AIFM33
9869SETDB13
4036LRP25
5241PGR3
843CASP103
3069HDLBP3
390502SERPINA23
5079PAX53
10863ADAM282
6598SMARCB11
23213SULF16
5218CDK143
10142AKAP92
7253TSHR2
3841KPNA53
57172CAMK1G3
22821RASA39
6455SH3GL13
79934COQ8B5
54822TRPM73
943TNFRSF83
114783LMTK33
1387CREBBP3
10454TAB13
3727JUND4
23225NUP2103
2313FLI15
10013HDAC63
31ACACA3
9699RIMS22
5966REL2
9411ARHGAP298
85021REPS12
10438C1D5
3456IFNB16
9024BRSK23
5166PDK41
55300PI4K2B3
10215OLIG23
4851NOTCH13
5314PKHD11
10295BCKDK2
9578CDC42BPB1
10746MAP3K25
25865PRKD25
25925ZNF5212
54477PLEKHA52
57670KIAA15494
22861NLRP12
837CASP42
440279UNC13C2
816CAMK2B3
84033OBSCN3
5607MAP2K55
11073TOPBP12
2051EPHB62
9693RAPGEF22
57787MARK45
222484LNX23
1586CYP17A18
3091HIF1A3
4005LMO23
6041RNASEL3
9175MAP3K133
200576PIKFYVE2
80351TNKS23
6733SRPK24
6091ROBO16
2042EPHA35
23255MTCL13
9636ISG151
11169WDHD13
1936EEF1D3
83990BRIP16
284217LAMA13
269AMHR22
83931STK402
4982TNFRSF11B2
2045EPHA72
23405DICER12
1992SERPINB13
399979SNX193
65217PCDH153
286826LIN96
23191CYFIP13
23387SIK35
4294MAP3K103
7525YES13
1973EIF4A13
50488MINK13
2068ERCC23
5591PRKDC2
80312TET12
79705LRRK12
5568PRKACG5
8091HMGA23
6098ROS13
9472AKAP62
638BIK3
3685ITGAV3
8945BTRC2
1009CDH116
2521FUS2
3397ID12
5924RASGRF23
2734GLG13
84433CARD113
6792CDKL52
7010TEK6
7533YWHAH6
5450POU2AF11
898CCNE18
23152CIC2
2066ERBB41
5327PLAT3
5863RGL22
10290SPEG4
1029CDKN2A5
5108PCM16
28514DLL12
6092ROBO24
4602MYB2
79058ASPSCR12
6714SRC1
6794STK114
57194ATP10A4
3791KDR4
10114HIPK33
6772STAT13
93210PGAP34
3000GUCY2D3
2263FGFR23
8408ULK13
84075FSCB2
105ADARB23
344387CDKL43
8874ARHGEF76
1555CYP2B61
51086TNNI3K1
5600MAPK112
2309FOXO32
8660IRS23
57188ADAMTSL32
57105CYSLTR22
65125WNK12
136332LRGUK3
4436MSH22
6035RNASE13
7175TPR3
80205CHD93
4026LPP5
8997KALRN3
6795AURKC9
2071ERCC33
57111RAB251
54658UGT1A11
6654SOS14
7204TRIO3
5297PI4KA2
10769PLK26
30827CXXC13
5578PRKCA1
4214MAP3K19
3702ITK3
9972NUP1532
3239HOXD133
50615IL21R2
5290PIK3CA6
3720JARID26
5034P4HB6
26524LATS23
253260RICTOR3
6391SDHC3
5045FURIN1
64919BCL11B3
2030SLC29A13
675BRCA21
607BCL92
4803NGF2
10155TRIM283
7075TIE12
1956EGFR3
4609MYC3
64333ARHGAP92
11064CNTRL3
5789PTPRD1
8795TNFRSF10B1
4684NCAM13
26278SACS7
29951PDZRN45
5663PSEN12
5187PER14
7917BAG62
375056MIA33
137872ADHFE17
3949LDLR2
23005MAPKBP14
7153TOP2A2
57082KNL11
84630TTBK18
1213CLTC3
22976PAXIP12
83452RAB33B6
57538ALPK33
5598MAPK71
8924HERC22
339345NANOS26
6095RORA3
29844TFPT3
7301TYRO31
8029CUBN2
9113LATS14
7849PAX83
9321TRIP113
1230CCR15
9509ADAMTS21
10752CHL15
23476BRD43
51330TNFRSF12A3
1487CTBP13
140609NEK73
8888MCM3AP3
667DST3
1974EIF4A23
4004LMO11
140803TRPM63
2324FLT44
85409NKD22
9344TAOK23
23090ZNF4233
3899AFF33
7273TTN2
1445CSK3
79834PEAK12
5582PRKCG2
85415RHPN23
23389MED13L6
8028MLLT103
6787NEK46
8667EIF3H6
54904NSD32
387RHOA6
29941PKN34
3161HMMR2
2046EPHA82
10243GPHN8
8805TRIM246
8394PIP5K1A3
344905ATP13A52
51151SLC45A23
3611ILK3
7248TSC13
3297HSF13
5562PRKAA13
2690GHR1
2317FLNB6
8031NCOA43
10111RAD501
6790AURKA3
1789DNMT3B3
53353LRP1B6
7094TLN15
5609MAP2K72
1281COL3A15
9201DCLK12
2185PTK2B3
63976PRDM165
5335PLCG12
131890GRK73
2194FASN3
598BCL2L12
57448BIRC64
8317CDC72
3717JAK29
7099TLR43
7227TRPS12
53335BCL11A3
5506PPP1R3A3
79837PIP4K2C4
57118CAMK1D3
4221MEN13
8428STK243
4772NFATC12
51562MBIP1
4261CIITA3
4330MN12
182JAG11
7046TGFBR11
80781COL18A14
4974OMG5
5925RB15
2065ERBB33
25ABL13
862RUNX1T12
7403KDM6A1
1432MAPK149
112268437LOC1122684372
4205MEF2A3
3716JAK13
3488IGFBP52
3480IGF1R2
4915NTRK23
2261FGFR33
23072HECW13
3237HOXD113
5567PRKACB4
4040LRP64
55422ZNF3314
581BAX1
3092HIP12
156GRK23
4763NF13
57697FANCM2
1612DAPK14
9625AATK3
63893UBE2O6
1840DTX12
4591TRIM375
10891PPARGC1A3
440270GOLGA8B3
2044EPHA55
5287PIK3C2B1
3110MNX13
3679ITGA73
6943TCF213
1608DGKG2
7294TXK2
6868ADAM173
23112TNRC6B4
27255CNTN63
1499CTNNB13
2444FRK8
3440IFNA212
2892GRIA35
4916NTRK36
1795DOCK33
167359NIM1K1
5624PROC2
5970RELA6
5590PRKCZ2

Gene in drug-gene network: Network Plot

Models in MST-312

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